Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (18): 3389-3392.doi: 10.3969/j.issn.1673-8225.2010.18.039

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Peritonitis complicated with continuous ambulatory peritoneal dialysis: Analysis of 108 cases in 3 years

Wang Qing-hua1, Yuan Fang2, Li Qiang-xiang3, Zhang Zhuo1, Chen Jing-jing1   

  1. 1 Loudi Central Hospital, Loudi   417000, Hunan Province, China; 2 Department of Nephrology, Second Xiangya Hospital, Central South University, Changsha  410000, Hunan Province, China; 3 Post doctoral Research Station, Institute of Political Science and Administration, Central South University, Changsha  410083, Hunan Province, China
  • Online:2010-04-30 Published:2010-04-30
  • Contact: Yuan Fang, Attending physician, Department of Nephrology, Second Xiangya Hospital. Central South University, Changsha 410000, Hunan Province, China Correspondence to: Li Qiang-xiang, Doctor, Master’s supervisor, Chief physician, Postdoctoral Research Station, Institute of Political Science and Administration, Central South University, Changsha 410083, Hunan Province, China yuanfangcat@21cn.com
  • Supported by:

    the Foundation of Health Department of Hunan Province, No. B 2006-215*; the Science and Technology Bureau of Loudi City, No. [2007]15*; Hunan Postdoctoral Scientific Program, No. 200944*

Abstract:

BACKGROUND: Peritonitis is the common detective complications at the end-stage of renal failure patients during continuous ambulatory peritoneal dialysis (CAPD) treatment, which easily repeatedly occurred if not handled properly. Although the plumbing designs of peritoneal dialysis have done a lot of effort and improved in recent years, it still hard to avoid. 
OBJECTIVE: To explore the relative factors and treatments of infectious peritonitis complicated with CAPD.
METHODS: Totally 115 cases received CAPD were selected, including 55 males and 60 females, aged (56.2±8.7) years. 68 cases of which were suffered infectious peritonitis, aged (58.5±8.3) years. All received a (30.3±5.5)-month CAPD treatment. The relative factors such as the nutrition situation, whether complicated with diabetes mellitus or not, culture background, domestic environment, whether operating by special person and so on were investigated, and the relationship between those factors and infectious peritonitis were analyzed. The pathogen method was used to check pathogenic bacteria, and those patients were treated with irrigation of abdominal cavity and antibiotics in two ways, that is, systemic and intra-abdominalcavity. Hemodialysis instead of CAPD was used in those infectious peritonitis patients.
RESULTS AND CONCLUSION: Those patients with good nutrition situation, higher culture background, better domestic environment, and operating by special person had low chances to infect peritonitis. And those patients with diabetes mellitus had high chances to infect peritonitis. Treatments of abdominal cavity and anti-infection in two ways-systemic and intra-abdominal cavities were effective to those infectious peritonitis patients. Gram-positive bacteria were the most common pathogen, which were susceptive to vancomycin and cefazolin. If the pathogen was gram-negative bacteria, etimicin sulfate, amikacin, and imipenem cilastatin could be selected. Infectious peritonitis complicated with CAPD affected by many factors. CAPD patients should be provided better nutrition and domestic situation. Also patients should operate in aseptic ways. Doctors should choose proper patients who can operate CAPD right.

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