Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (4): 585-588.doi: 10.3969/j.issn.1673-8225.2010.04.004

Previous Articles     Next Articles

Computer-aided artificial prosthetic replacement for acetabular tumor

Liang Wen-qing, Zheng Long-po, Cai Zheng-dong, Li Jian, Hua Ying-qi   

  1. Department of Orthopaedics, First Affiliated Hospital of Second Military Medical University of Chinese PLA, Shanghai  200433, China
  • Online:2010-01-22 Published:2010-01-22
  • Contact: Cai Zheng-dong, Department of Orthopaedics, First Affiliated Hospital of Second Military Medical University of Chinese PLA, Shanghai 200433, China CZD856@vip.sohu.com
  • About author:Liang Wen-qing☆, Doctor, Attending physician, Department of Orthopaedics, First Affiliated Hospital of Second Military Medical University of Chinese PLA, Shanghai 200433, China chyygklwq@hotmail.com

Abstract:

BACKGROUND: There are disputes concerning limb salvage and reconstruction in treating pelvis malignant tumor.   
OBJECTIVE: To study the surgical treatment following resection of tumor at acetabular region in order to restore pelvic stability with less damage or recurrence.
METHODS: Thirty-three patients diagnosed with pelvic tumor at Department of Orthopaedics, First Affiliated Hospital of Second Military Medical University from April 2002 to June 2008 were selected. All patients were received tumor resection and computer-aided prosthetic replacement, 18 patients (8 cases with chondrosarcoma, 2 cases with Ewing sarcoma, 2 cases with osteosarcoma, and 6 cases with malignant fibrous histiocytoma) were combined with antitumor drug treatment. Functional assessment of therapeutic efficacy was divided into 4 levels: excellent, good, moderate, and inferior.
RESULTS AND CONCLUSION: Two patients died at months 4 and 6 after prosthetic replacement; 31 cases were followed-up for 8-32 months, mean 12.5 months. Seven cases were recurred chondrosarcoma, the recovery of other patients were as follow: 18 cases were excellent, 4 cases were good, 2 cases were moderate and no case was inferior. Most of limb function and pelvic stability was preserved. The results suggested that malignant fibrous histiocytoma and Ewing sarcoma can receive a high rate of limb preservation if treated by effective chemotherapy with low recurrence; the recurrence of chondrosarcoma was high. Tumor resection combined with computer-aided prosthetic replacement can maximatily reserve limb function and raise life quality.

CLC Number: