Chinese Journal of Tissue Engineering Research ›› 2023, Vol. 27 ›› Issue (36): 5818-5822.doi: 10.12307/2023.757

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Total disc replacement for cervical spondylosis with sympathetic symptoms

Ma Hui1, Jia Xiangyuan2, Yang Haotian1, Yuan Lin1, Li Yafeng1, Zhao Xueqian3, Jia Yusong3   

  1. 1Department of Orthopedics and Traumatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China; 2Department of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China; 3Department of Orthopedics, Yuquan Hospital, Tsinghua University (Tsinghua University Integrated Hospital of Traditional Chinese and Western Medicine), Beijing 100040, China 
  • Received:2022-11-04 Accepted:2022-12-29 Online:2023-12-28 Published:2023-03-24
  • Contact: Jia Yusong, MD, Chief physician, Professor, Doctoral supervisor, Department of Orthopedics, Yuquan Hospital, Tsinghua University (Tsinghua University Integrated Hospital of Traditional Chinese and Western Medicine), Beijing 100040, China Zhao Xueqian, Master, Physician, Department of Orthopedics, Yuquan Hospital, Tsinghua University (Tsinghua University Integrated Hospital of Traditional Chinese and Western Medicine), Beijing 100040, China
  • About author:Ma Hui, Master candidate, Department of Orthopedics and Traumatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
  • Supported by:
    Horizontal Scientific Research Project (Biomechanics and Animal Experimental Research of the New Cervical Anterior and Posterior Internal Fixation System), No. HX-DZM-2017001 (to JYS)

Abstract: BACKGROUND: The treatment of cervical spondylosis with total disc replacement can retain the range of motion of the cervical lesion segment and can effectively improve the symptoms of cervical spondylosis with sympathetic symptoms. 
OBJECTIVE: To investigate the clinical efficacy of total disc replacement for cervical spondylosis with sympathetic symptoms. 
METHODS: Retrospective analysis was made on 56 patients with cervical spondylosis with obvious sympathetic symptoms such as dizziness and headache who were operated on from December 2018 to December 2021. The sagittal parameters of the cervical spine before, 3 months after surgery and at the last follow-up were observed and compared, including cervical sympathetic symptom score and Japanese Orthopaedic Association Scores, operation segment angle, C2-C7 Cobb angle, C2-C7 sagittal vertical axis and T1 slope. The correlation between the changes in sympathetic symptoms and Japanese Orthopaedic Association Scores before and after surgery and the changes in cervical sagittal parameters before and after surgery was analyzed. 
RESULTS AND CONCLUSION: (1) All patients showed improvement in sympathetic symptoms after surgery, and the sympathetic symptom scores and Japanese Orthopaedic Association Scores were significantly improved at 3 months and at the last follow-up compared with those before surgery (P < 0.05), but Japanese Orthopaedic Association Scores did not show significant differences at the last follow-up compared with those at 3 months after surgery (P > 0.05). (2) The cervical sagittal parameters increased at 3 months and at the last follow-up compared with those before surgery, but not at the last follow-up compared with those at 3 months after surgery (P > 0.05). (3) The pre- and post-operative change values of sympathetic symptom scores significantly correlated with the pre- and post-operative change values of operation segment angle and C2-7 Cobb angle (P < 0.05). (4) The results indicate that total disc replacement has a good effect in the treatment of cervical spondylosis with sympathetic symptoms, which is conducive to restoring the sagittal parameters of the cervical spine and alleviating the sympathetic symptoms of patients. 

Key words: cervical spondylosis, total disc replacement, sympathetic symptom, sagittal parameter, cervical vertebra, artificial prosthesis

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