Abstract:

BACKGROUND: The rebuilding and repair of the urethra need not only the appropriate material, but also a new craft and scaffold shape. The new configuration can simulate the shape of the urethra, and will provide a positive environment for cell growth.
OBJECTIVE: To explore the preparation of polyglycolic acid (PGA) as the braiding urethral scaffold material.
METHODS: The 48tex PGA filament was used as the urethral scaffold material, which was composed of 7 multifilaments, without twist. Each multifilament contained 12 single fibers. 2D-3 axis technics was utilized at 95 ℃, heat setting for 5 minutes. Following heat setting, impregnation method was used to coat for 30 minutes. Following drying in the open air, the sample was frozen and dried for 4 hours.
RESULTS AND CONCLUSION: The textile knitting technology was firstly used for bionic stimulation molding. Porosity of PGA braiding urethral scaffold is over 90%, which can meet the requirement of urethral porosity.