Abstract:

BACKGROUND: Rare earth elements have some biological effects, and broad-spectrum anti-bacterial, anti-inflammatory and anti-virus capabilities, they can increase the bonding strength.
OBJECTIVE: To introduce rare earth lanthanum into the implant coating, and to evaluate the biocompatibility of ultrasound-assisted micro-arc oxidation preparing the lanthanum biocoating.
METHODS: Using ultrasound-assisted micro-arc oxidation, the biocoating containing lanthanum was prepared on the surface of the near β-type titanium alloy, and implanted in rabbit femur. The titanium alloy matrix and the micro-arc oxidation biocoating without lanthanum served as the control group. Optical microscope was used to observe the formation of new bone; Scanning electron microscopy was applied to observe the combination interface of implant and bone, and the bone residue after pulling the implant; the bone contact rate was statistically analyzed.
RESULTS AND CONCLUSION: In the experimental group, the new bone formed surrounding the implant without any fibers and osteoclasts; Scanning electron microscopy and bone contact rate are the best in the experimental group and the worst in the titanium alloy group. This shows that ultrasound-assisted micro-arc oxidation preparing the lanthanum biocoating can achieve high osseointegration and good biocompatibility．