中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (29): 5455-5458.doi: 10.3969/j.issn.1673-8225.2010.29.034

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

生物材料与踝关节损伤生物力学特点及应用

郭建营   

  1. 河南理工大学体育学院，河南省焦作市  454000
  • 出版日期:2010-07-16 发布日期:2010-07-16
  • 作者简介:郭建营★，男，1977年生，河南省焦作市人，汉族，2000年河南师范大学毕业，硕士，主要从事运动训练与体育保健学研究。

Application of biomaterials and biomechanical characteristics of ankle injuries

Guo Jian-yin   

  1. College of Physical Education, Henan University of Technology, Jiaozuo   454000, Henan Province, China
  • Online:2010-07-16 Published:2010-07-16
  • About author:Guo Jian-ying★, Master, College of Physical Education, Henan University of Technology, Jiaozuo 454000, Henan Province, China

PDF

920

被引次数

13

摘要：

目的：探讨踝关节损伤的生物力学特点及生物材料的干预治疗情况，对踝关节损伤后治疗手段与机制进行分类与归纳。
方法：作者应用计算机检索PubMed数据库(http://www.ncbi.nlm.nih.gov/PubMed) 1998/2007及CNKI数据库(www.cnki. net/ index.htm)2003/2009的文章，在标题和摘要中以“踝关节，损伤，生物材料，治疗”或“Ankle Joint, Injury, Biological Materials, Treatment”为检索词进行检索。选择与踝关节损伤、治疗手段、材料学特点及其生物相容性等相关的文章，共纳入22篇。
结果：踝关节是人体弹跳启动器，也是落地缓冲装置，由于运动中存在多种内外部因素致使踝关节韧带损伤较为常见。目前踝关节韧带康复疗法中多为物理疗法和手术修复，或两者相结合进行治疗。随着现代医学的不断进步，目前运用生物材料干预肌腱损伤后的愈合手段日趋成熟。
结论：由于踝关节作为负重关节，关节遭受暴力较大，以及受力复杂等因素，踝关节对韧带功能恢复要求更高，所以这将成为生物材料在踝关节韧带损伤康复运用工程中面临的难题。目前研究人员在韧带材料的选择、处理以及材料表面修饰等多方面的尝试使其能够模拟自体韧带的功能，已取得了较好的效果。随着细胞生物学、分子生物学方法和技术的进步，以及基因疗法等方法的运用，肌腱韧带损伤修复的研究必将进入崭新阶段，也为踝关节韧带生物材料的妥善运用提供了可能和依据。

关键词: 踝关节, 损伤, 生物力学, 肌腱, 生物材料, 治疗

Abstract:

OBJECTIVE: To investigate the biomechanical characteristics of ankle joint injury and biomaterial intervention treatment, to classify and summarize the treatment means and mechanisms after ankle joint injury.
METHODS: A computer search was conducted on PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) from 1998 to 2007 and CNKI Database (www.cnki.net / index.htm) from 2003 to 2009, using “ankle joint, injury, biological materials, treatment” in English and in Chinese as key words in the title and summary. Articles about ankle joint injury, treatment, material science characteristics and biocompatibility were included, totally 22 articles.
RESULTS: The ankle joint is the bounce starter of human body, also the landing buffer unit. Ankle ligament injury is common because of several internal and external factors in exercise. Currently ankle ligament rehabilitation therapy is physical therapy and surgical repair, or a combination treatment of the two. With the advances of modern medicine, the biomaterial intervention of tendon healing is developing.
CONCLUSION: Because the ankle joint is a weight-bearing joint, bearing large violence, and other factors such as complex stress, ankle joint requires a high ligament function, which is a potential problem of applying biomaterials on ankle ligament injury rehabilitation. Current researches have achieved good results in simulating the function of autologous ligament through many tries such as ligament material selection, processing and surface modification. With the advancement of cell biology, molecular biology methods and technologies, as well as the use of gene therapy, the studies on the repair of tendon ligament injury will enter a new phase, also provides possibility and evidence for proper use of biomaterials for ankle ligament.

中图分类号: