中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (22): 4105-4108.doi: 10.3969/j.issn.1673-8225.2010.22.029

• 骨与关节学术探讨 academic discussion of the bone and joint • 上一篇    下一篇

人工关节置换后的深静脉血栓形成

柳  椰，潘  梁   

  1. 沈阳市骨科医院，辽宁省沈阳市  110044
  • 出版日期:2010-05-28 发布日期:2010-05-28
  • 作者简介:柳 椰，男，1971年生，辽宁省新民市人，汉族，1995年沈阳医学院毕业，副主任医师，主要从事骨科临床医疗及医院行政管理工作。 sy_gkyy@163.com

Deep venous thrombosis following artificial joint replacement 

Liu Ye, Pan Liang   

  1. Shenyang Orthopedics Hospital, Shenyang   110044, Liaoning Province, China
  • Online:2010-05-28 Published:2010-05-28
  • About author:Liu Ye, Associate chief physician, Shenyang Orthopedics Hospital, Shenyang 110044, Liaoning Province, China

PDF

498

被引次数

20

摘要：

目的：探讨深静脉血栓形成的病因及预防诊疗情况。
方法：应用计算机检索维普数据库与人工关节置换后深静脉血栓形成及预防有关的文献。检索时限为1998-01/2009-10。检索关键词：深静脉血栓形成；病因；诊断；预防。对资料进行初审，并查看每篇文献后的引文，共入选相关文献26篇。
结果：关节置换后深静脉血栓与年龄、性别、癌症病史、既往深静脉血栓病史、肥胖指数、麻醉术式、骨水泥因素、手术及创伤等多种因素有关，预防血栓除卧床休息，抬高患肢等一般治疗外，还需采用抗凝、溶栓和手术取栓等多种方法治疗。现多提倡联合应用2种或3种方法来预防深静脉血栓的发生。
结论：早期深静脉血栓监测以及系统性抗凝预防深静脉血栓非常重要。目前仍然没有一种药物(或联合应用)能够完美解决人工关节置换后深静脉血栓的问题，最佳药品及用药方式仍需要进一步研究。

关键词: 深静脉血栓形成, 人工关节, 病因, 诊断, 预防

Abstract:

OBJECTIVE: To explore the cause and prevention of deep venous thrombosis.
METHODS: A computer-based online search of VIP database was performed for articles related to the formation and prevention of deep venous thrombosis following artificial joint replacement, published between January 1998 and October 2009, with the key words “deep venous thrombosis, cause, diagnosis, prevention”. The data were collected, and references of each article were reviewed. A total of 26 articles were included.
RESULTS: Deep venous thrombosis following joint replacement is related to age, gender, cancer history, previous thrombosis, obesity index, anesthesia approach, bone cement, operation and trauma. Bed rest, affect limb raising, anticoagulation, thrombolysis and thrombus removal by operation can be used to prevent thrombus. The combination of above two or three methods has been recommended.
CONCLUSION: Monitor of early deep venous thrombosis and systematic anticoagulation are important for venous thrombosis prevention. However, there remains no medicine (or combination application) that can treat deep venous thrombosis following joint replacement. The best medicine and medication pattern require further exploration.

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