Digit and digit ratio of Xinjiang young Kazakh nationality

doi:10.3969/j.issn.2095-4344.2014.42.028

Abstract

Abstract:

BACKGROUND: Digit ratio is basically determined within the first 3 months of fetal development. Digit and digit ratio exhibit differences between genders and between left and right hands. Nationality, regional and ethnic difference may also influence the digit ratio. So far, there is no report about the digit ratio of Kazakh adults.
OBJECTIVE: To study the characteristics of digit ratio of young Kazakh nationality in Xinjiang of China.
METHODS: A total of 200 young Kazakh volunteers in Xinjiang, aged 18-25 years, were enrolled, including 100 males and 100 females. These participants were subjected to posteroanterior X-ray of both hands. Phalanx length and body height were measured, and the resulting data were statistically analyzed using SPSS19.0 software.
RESULTS AND CONCLUSION: The digit ratio of Xinjiang Kazakh people was 3D > 4D > 2D > 5D. Male digit ratio possessed the tendency of 3D:5D > 4D:5D > 2D:5D > 3D:4D > 3D:4D > 2D:3D > 2D:4D; female digit ratio possessed the tendency of 3D:5D > 2D:5D > 3D:4D > 4D:5D > 2D:4D > 2D:3D. The digit ratio of 2D:3D, 3D:4D, 4D:5D was higher in the male than the female; the digit ratio of 2D:4D, 2D:5D, 3D:5D was higher in the female than the male. Digit ratio had sexual differences, especially in 3D:5D (P < 0.05), and had bilateral differences, especially in 2D:4D and 4D:5D (P < 0.05). These findings indicate that the digit ratio of Xinjiang Kazakh people exhibits a bilateral difference, especially in 2D:4D and 4D:5D, as well as a sexual difference, especially in 3D:5D.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

全文链接：

Key words: adult, finger injuries, thumb, humans, fingers

CLC Number:

R318

Nuermaimaiti Bahaxiaer, Ai Hua, Wu Hai-zhong . Digit and digit ratio of Xinjiang young Kazakh nationality[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(42): 6878-6883.

Figures/Tables 2

References

[1] Manning JT, Scutt D, Wilson J, et al. The ratio of 2nd to 4th digit length: a predictor ofsperm numbers and concentrations of testosterone, luteinizing hormone and oestrogen. Hum Reprod. 1998;13:3000-3004.
[2] Manning JT, Bundred P. The ratio of 2nd to 4th digit length:a new predictor of disease predisposition. Med Hypotheses. 2000;54(5):855-857.
[3] Williams TJ, Pepitone ME, Christensen SE, et al. Finger-length ratio and sexual orientation. Nature. 2000; 404:455-456.
[4] Brown WM, Hines M, Fane BA, et al. Masculinized finger length patterns in human malesand females with congenital adrenal hyperplasia. Horm Behav. 2002;42(4):380-386.
[5] Mclntyre MH, Cohn BA, Ellison PT. Sex dimorphism in digital for mulae of children. Am J Phys Anthropol. 2006;129(1): 143-150.
[6] McIntyre MH. The use of digit ratios as markers for perinatal and rogenaction. Reprod Biol Endocrinol. 2006;26:4-10.
[7] Manning JT, Barley L, Walton J, et al. The 2nd: 4th digit ratio, sexual dimorphism, population differences,and reproductive success: evidence for sexually antagonistic genes. Evol Hum Behav. 2000;21:163-183.
[8] Manning JT, Henzi P, Venkatramana S. Second to fourth digitratio ethnic differences and family size in English, Indian and South African populations. Ann Hum Biol. 2003;30(5): 579-588.
[9] Manning JT, Henzi P, Bundred PE. The ratio of 2nd to 4th digit length: a proxy fortestosterone, and susceptibility to HIV and AIDS. Med Hypotheses. 2001;57(6):761-763.
[10] Manning JT, Callow MP, Bundred E. Finger and toe ratios in humans and mice: implications fortheaetiology ofdiseases influenced byHOX genes. Med Hypotheses. 2003;60(3): 340-343.
[11] Ronalds GW, Phillips Dl, Godfrey KM, et al. The ratio of second to fourth digit length: amarker of impaired fetal growth. Early Hum Dev. 2002;70:21-26.
[12] Phillips GB, Pinkemell BH, Jing TY. The association of hypotesteronemia with conronary artery diseases in men. Aterioscler Thromb. 1994;14(5):701-706.
[13] 陆宏,霍正浩,张科静,等.指长比与冠心病的相关性研究[J].解剖学报,2008,39(5):765-768.
[14] 陆宏,霍正浩,陈静等.指长比与乳腺癌的相关性研究[J].人类学学报,2008,27(4):359-363.
[15] 罗桐秀,黄春霞.人类HOX基因改变导致肢体畸形的研究进展[J].国外医学遗传学分册,2005,28(2):105-108.
[16] Goodman FR, Scambler PJ. Human HOX gene mutations. Clin Genet. 2001;59(1):1-11.
[17] Peichel CL, Prabhakaran B, Vogt TF. The mouse Ulnaless mutation deregulates posterior HoxD gene expression and alters appendicular patterning. Development. 1997;124(18): 3481-3492.
[18] Herault Y, Fradeau N, Zakany JU. A regulatory mutation in ducing both loss-of-function of posterior Hoxd genes. Development. 1997;124(18):3493-3500.
[19] 梁艳明,席焕久,李明,等.人类指长比的研究进展[J].解剖科学进展,2008,14(4):449-452.
[20] Manning JT, Bundred PE, Flanagan BF. The ratio of 2nd to 4nd digit length:a proxy for transaction activityof the androgen receptorgene. Medical Hypotheses. 2002;59(3):334-336.
[21] 席焕久,胡荣,温有锋,等.辽宁汉族指长及指长比的特点[J].解剖学报,2010,41(3):471-479.
[22] 王景靓,徐飞,李岩,等.大连汉族群体的指长比特点[J].解剖学报, 2010,41(5):751-755.
[23] 努尔买买提•巴哈夏尔,董建江,爱华,等.哈萨克族成人掌骨的X线测量与身高的回归分析[J].解剖学杂志,2010,33(6):802-805.
[24] 努尔买买提•巴哈夏尔,董建江,爱华,等.哈萨克族成人掌骨的X线测量及其与身高的性别判别分析[J].解剖学报,2010,41(1): 151-154.
[25] 李建福,骆文斌,余跃生,等.布依族群体指长比的研究[J].现代预防医学,2011,38(1):97-99.
[26] 努尔买买提•巴哈夏尔,爱华,吴海忠,等.哈萨克族成人指骨长度与身高的性别判别[J].解剖学报,2013,44(5):736-740.
[27] 努尔买买提•巴哈夏尔,凯赛尔江•多来提,爱华,等.新疆哈萨克族成人指骨长度与身高的逐步回归分析[J].东南大学学报(医学版), 2013,32(5):591-594.
[28] 孙进,李岩,徐飞.鞍山市304名汉族成人手部44项形态学指标特点[J].中国组织工程研究与临床康复,2007,11(6):1099-1105.
[29] 马坚妹,徐飞,赵薇,等.辽宁汉族青年手的体质人类学研究一手指部分[J].大连医科大学学报,1999,21(4):300-302.
[30] 王衡,关华忠,龚鹏鸣.维吾尔族手的测量与指型观察[J].人类学学报,1985,4(1):80-93.
[31] 陆宏,霍正浩,师志云,等.宁夏回族和汉族群体指长比的研究[J].解剖学报,2008,39(2):267-271.
[32] Vehmas T, Soiovieva S, Leino-arjas P. Radiographic 2D:4D index in females: no relation to anthropometric, behavioural, nutritional, health-related, occupational or fertility variables. J Negat Resuits Biomed. 2006;5:12-19.
[33] Lee Y, Lee JY, Kim MH. PI3K/Akt pathway regulates retinoic acid-induced Hox gene expression in F9 cells. Dev Growth Differ. 2014;56(7):518-25.
[34] Pradeepa MM, Grimes GR, Taylor GC, et al. Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins. Nucleic Acids Res. 2014;42(14): 9021-9032.
[35] Bhatlekar S, Fields JZ, Boman BM. HOX genes and their role in the development of human cancers. J Mol Med (Berl). 2014; 92(8):811-823.
[36] Martin KJ, Holland PW. Enigmatic orthology relationships between hox clusters of the african butterfly fish and other teleosts following ancient whole-genome duplication. Mol Biol Evol. 2014;31(10):2592-2611.
[37] Bacino CA, Hecht JT. Etiopathogenesis of equinovarus foot malformations. Eur J Med Genet. 2014;57(8):473-479.
[38] Woltering JM, Noordermeer D, Leleu M, et al. Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits. PLoS Biol. 2014;12(1):e1001773.
[39] Berlivet S, Paquette D, Dumouchel A, et al. Clustering of tissue-specific sub-TADs accompanies the regulation of HoxA genes in developing limbs. PLoS Genet. 2013;9(12): e1004018.
[40] Tsumagari K, Baribault C, Terragni J, et al. DNA methylation and differentiation: HOX genes in muscle cells. Epigenetics Chromatin. 2013;6(1):25.
[41] Sheth R, Bastida MF, Kmita M, et al. “Self-regulation,” a new facet of Hox genes' function. Dev Dyn. 2014;243(1):182-191.
[42] Sheth R, Grégoire D, Dumouchel A, et al. Decoupling the function of Hox and Shh in developing limb reveals multiple inputs of Hox genes on limb growth. Development. 2013; 140(10):2130-2138.