Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (16): 3025-3028.doi: 10.3969/j.issn.1673-8225.2012.16.039

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Application of poly (D, L-lactic acid) absorbable medical film in tendon repair

Xu Hai-dong, Zhao Jian-ning, Lu Jun-hao, Liu Jin-long, Chen Yong   

  1. Department of Orthopedics, Nanjing General Hospital of Nanjing Military Command, Nanjing  210002, Jiangsu Province, China
  • Received:2011-10-01 Revised:2011-12-07 Online:2012-04-15 Published:2012-04-15
  • Contact: Chen Yong, Master, Associate chief physician, Associate professor, Department of Orthopedics, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, Jiangsu Province, China 13813889089@139.com
  • About author:Xu Hai-dong★, Master, Attending physician, Lecturer, Department of Orthopedics, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, Jiangsu Province, China xuhaidong1980@163.com

Abstract:

BACKGROUND: The present studies are focused on how to reduce or eliminate adhesion after tendon repair to fulfill sliding function soon without affecting the healing of tendon.
OBJECTIVE: To observe the anti-adhesion effects of poly (D, L-lactic acid) (PDLLA) absorbable medical film on tendon repair.
METHODS: Sixty patients with flexor tendon and stretch tendon rupture (95 tendons) in hand selected from Nanjing General Hospital of Nanjing Military Region were randomly divided into two groups. Anastomosis 1.5-2.0 cm was wrapped by using Hongjian medical membrane in anti-adhesion biomembrance group, while control group did not use biological absorbable medical film. At 6 months after repair, flexor tendon and stretch tendon were detected by using total active movement system and Miller classification respectively for the comparison of comprehensive good rate.
RESULTS AND CONCLUSION: The comprehensive good rate in the anti-adhesion biomembrance group (90%, 45/50) was higher than that in the control group (67%, 30/45) during over 6-month follow-up after repair. It is indicated that the clinical application of PDLLA absorbable medical film is easy and convenient to reduce postoperative adhesion effectively after tendon repair, and its clinical effects are confirmed.
 

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