Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (39): 7380-7384.doi: 10.3969/j.issn.2095-4344.2012.39.032

Previous Articles     Next Articles

Relationship between deoxypyridinoline/creatinine and Singh index in elderly hip fracture patients

Hao Wei1, Yang Tie-yi2, Zhang Yan2, Liu Yue2, Shao Jin2   

  1. 1Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China
    2Department of Orthopedics, Shanghai Pudong New Area Gongli Hospital, Shanghai 200135, China
  • Received:2012-07-09 Revised:2012-07-25 Online:2012-09-23 Published:2012-09-23
  • Contact: Yang Tie-yi, Chief physician, Department of Orthopedics, Shanghai Pudong New Area Gongli Hospital, Shanghai 200135, China yang.tieyi@yahoo.com.cn
  • About author:Hao Wei★, Studying for master’s degree, Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China haoweiys@yeah.net

PDF

553

Cited

3

Abstract:

BACKGROUND: The deoxypyridinoline and creatinine ratio (DPD/Cr) and Singh index are widely used in measuring bone strength and bone lost in clinic, but the relationship between them is rarely reported.
OBJECTIVE: To analyze the relationship between DPD/Cr and Singh index in elderly hip fracture patients.
METHODS: A total of 100 samples over the age of 60 were collected from patients suffered fresh femoral neck fracture and intertrochanteric fracture. The deoxypyridinoline, urinary creatinine and Singh index were measured, and the relationship between DPD/Cr and Singh index was calculated.
RESULTS AND CONCLUSION: The DPD/Cr of 100 patients that suffered fresh femoral neck fracture and intertrochanteric fracture was (6.11±2.09) nmol/mmol; among them, 97 cases were higher than normal, and the other 3 cases were normal. The Singh index showed below grade IV in 91 cases, grade V in 9 cases. Spearman correlation analysis showed that the DPD/Cr in elderly hip fracture was negatively correlated with Singh index (r=-0.32, P=0.007). There was liner correlation between DPD/Cr and Singh index, the DPD/Cr and Singh index were consistent in the evaluation of bone quality.

CLC Number: