Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (8): 1501-1504.doi: 10.3969/j.issn.1673-8225.2012.08.038

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A 6-month follow-up of hyaluronate sodium intra-articular injection for the treatment of traumatic arthritis after ankle fracture

Ju Zhi-qing, Yang Xiao-hua, Jiang Gui-yun, Yang Xiao-lian   

  1. Department of Rehabilitation, Affiliated Hospital of Chengde Medical College, Chengde  067000, Hebei Province, China
  • Received:2011-11-15 Revised:2012-01-06 Online:2012-02-19 Published:2012-02-19
  • Contact: Yang Xiao-hua, Master, Associate chief physician, Master’s supervisor, Department of Rehabilitation, Affiliated Hospital of Chengde Medical University, Chengde 067000, Hebei Province, China cyfyyangxiaohua@ 163.com
  • About author:Ju Zhi-qing, Attending physician, Department of Rehabilitation, Affiliated Hospital of Chengde Medical College, Chengde 067000, Hebei Province, China ahju2000@163.com

Abstract:

BACKGROUND: Hyaluronate sodium is mainly used for the treatment of osteoarthritis; the traumatic arthritis after ankle fracture is mainly the degeneration of articular cartilage.
OBJECTIVE: To observe the therapeutic effect of hyaluronate sodium intra-articular injection on the treatment of traumatic arthritis after ankle fracture.
METHODS: Sixty patients with traumatic arthritis after ankle fracture were selected in the Department of Rehabilitation, Affiliated Hospital of Chengde Medical College from July 2009 to June 2011; the patients were treated with hyaluronate sodium intra-articular injection. The ankle pain, range of motion and traveled distance without pain were evaluated at 1 and 6 months after treatment.   
RESULTS AND CONCLUSION: Compared with pre-treatment, the visual analogue scale was significantly decreased (P < 0.01); the range of motion was increased, including angles of extensor expansion, plantar flexion, adduction, abduction, enstrophe (P < 0.01), as well as angles of extroversion (P < 0.05); traveled distance without pain was increased (P < 0.01). Hyaluronate sodium intra-articular injection can improve the clinical symptoms of traumatic arthritis after ankle fracture and the ankle function.

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