Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (3): 475-478.doi: 10.3969/j.issn.1673-8225.2012.03.021

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Inhibition effect of silver ion-loaded wollastonite coating on streptococcus mutans  

Jia Ying1, Liu Yan2, Qin Bo1, Wang Jin-sheng2   

  1. 1Department of Orthodontics, 2Department of Oral Medicine, Guiyang Medical College, Guiyang  550002, Guizhou Province, China
     
  • Received:2011-06-08 Revised:2011-08-16 Online:2012-01-15 Published:2012-01-15
  • Contact: Wang Jin-sheng, Associate chief physician, Department of Oral Medicine, Guiyang Medical College, Guiyang 550002, Guizhou Province, China
  • About author:Jia Ying★, Master, Associate professor, Department of Orthodontics, Guiyang Medical College, Guiyang 550002, Guizhou Province, China jiayingmed@218@ 189.cn
  • Supported by:

    Governor Foundation for Technological Talent of Guizhou Province, No. 2007-119*

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Abstract:

BACKGROUND: Coating material has no antibacterial. Implants containing coatings may result in infection after implantation   in vivo.
OBJECTIVE: To evaluate the inhibition effect of silver ion-loaded wollastonite coating on streptococcus mutans in vitro.
METHODS: The bacteriostatic annulus of silver ion-loaded wollastonite coating were measured using disc diffusion method in order to evaluate the antibacterial properties of the material.
RESULTS AND CONCLUSION: With the increase of the concentration of nitric acid silver, the silver ion in the coatings was increased. The bacteriostatic annulus of the 5% silver ion-loaded wollastonite group sustained for over 40 days, and the maximum diameter was bigger than those of the 1% silver ion-loaded wollastonite group and the none silver ion-loaded wollastonite group (P < 0.01). It is indicated that the silver ion-loaded wollastonite coating can slowly release Ag+ which can inhibit bacteria. The bacteriostatic efficiency of silver ion-loaded wollastonite coating and its duration time can be regulated in some degree by adding Ag+ solution of different initial concentrations into it.

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