Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (3): 459-462.doi: 10.3969/j.issn.1673-8225.2012.03.017

Previous Articles     Next Articles

Cellular biocompatibility of induced human bone marrow stromal cells to fluoride conversion coating magnesium alloys  

Jiang Hai-ying1, Yan Zheng-bin1, 2, Zhang Zhao3, Ai Hong-jun1   

  1. 1Department of Stomatology, Daqing Oilfield General Hospital, Daqing  163001, Heilongjiang Province, China; 2Oral Medicine College of Jiamusi University, Jiamusi  154002, Heilongjiang Province, China; 3Clinics of Guangzhou Sports Vocational College, Guangzhou  510650, Guangdong Province, China; 4Department of Prosthodontics, Affiliated Dental Hospital of China Medical University, Shenyang  110002, Liaoning Province, China
  • Received:2011-07-20 Revised:2011-11-08 Online:2012-01-15 Published:2012-01-15
  • Contact: Ai Hong-jun, Professor, Doctoral supervisor, Department of Prosthodontics, Affiliated Dental Hospital of China Medical University, Shenyang 110002, Liaoning Province, China
  • About author:Ai Hong-jun, Professor, Doctoral supervisor, Department of Prosthodontics, Affiliated Dental Hospital of China Medical University, Shenyang 110002, Liaoning Province, China
  • Supported by:

    Natural Science Foundation of Liaoning Province, No. 2008079*

PDF

369

Abstract:

BACKGROUND: As newly developed magnesium alloy, whether fluoride conversion coating and β-tricalcium phosphate (β-TCP) coating Biodegradable AZ31B magnesium alloy has better cell compatibility is not confirmed.
OBJECTIVE: To evaluate the cell compatibility of fluoride conversion coating and β-TCP coating Biodegradable AZ31B magnesium alloy tested with the induced human bone marrow stromal cells. 
METHODS: The experiment was divided into three groups: AZ31B magnesium alloy group, fluoride conversion coating AZ31B magnesium alloy group and β-TCP coating Biodegradable AZ31B magnesium alloy group. The induced human bone marrow stromal cells were regarded as the tested cells, and the extracts of the three materials were used in the compatibility experiments in vitro. 
RESULTS AND CONCLUSION: The toxicity of cells in the leaching liquor of fluoride conversion coating and β-TCP coating Biodegradable AZ31B magnesium alloys were Grade 1. The toxicity of cells in the leaching liquor of AZ31B magnesium alloys was Grade 2. This experiment had proved that the fluoride conversion coating and β-TCP coating Biodegradable AZ31B magnesium alloys were superior than AZ31B magnesium alloys .

CLC Number: