Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (3): 431-433.doi: 10.3969/j.issn.1673-8225.2012.03.011

Previous Articles     Next Articles

Fabrication and properties of nanometer hydroxyapatite/calcium polyphosphate/poly(L-lactic acid) composite scaffold for bone tissue engineering

Zhu Ling-yun, Wang Yan-ping, Shi Zong-li, Zhang Hong-mei   

  1. School of Mechatronic Engineering, Lanzhou Jiaotong University, Lanzhou  730070, Gansu Province, China
  • Received:2011-07-03 Revised:2011-08-30 Online:2012-01-15 Published:2012-01-15
  • About author:Zhu Ling-yun★, Master, Lecturer, School of Mechatronic Engineering, Lanzhou Jiaotong University, Lanzhou 730070, Gansu Province, China zhuly@mail.lzjtu.cn
  • Supported by:

    the Natural Science Foundation of Gansu Province, No. 096RJZA085*

PDF

392

Cited

4

Abstract:

BACKGROUND: Studies have achieved great progresses in compound materials for bone and cartilage tissue scaffolds. However, there are still some problems.
OBJECTIVE: To observe the fabrication and properties of nanometer hydroxyapatite/calcium polyphosphate/poly(L-lactic acid) (nanometer HAP/CPP/PLLA) composite scaffold for bone tissue engineering.
METHODS: Nanometer HAP/CPP/PLLA composite scaffold was prepared by solvent casting, particulate leaching combined with gas foaming. The properties of physical mechanics were tested.
RESULTS AND CONCLUSION: The experimental results showed that the composite scaffold had high porosity and compressive modulus as well as the three-dimensional, connectivity network microstructures. Therefore, this composite may be one of scaffold materials for bone tissue engineering with potentially broad applicability.

CLC Number: