Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (2): 345-348.doi: 10.3969/j.issn.1673-8225.2012.02.035

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Establishment and evaluation of an animal model of tractive spinal cord injury 

Wu Yue, Zou Guo-yao   

  1. Department of Spinal Surgery, Affiliated Hospital of Guilin Medical University, Guilin  541001, Guangxi Zhuang Autonomous Region, China
  • Received:2011-08-16 Revised:2011-11-09 Online:2012-01-08 Published:2012-01-08
  • Contact: Zou Guo-yao, Chief physician, Professor, Master’s supervisor, Department of Spinal Surgery, Affiliated Hospital of Guilin Medical University, Guilin 541001, Guangxi Zhuang Autonomous Region, China zhouguoyao2000@yahoo.com.cn
  • About author:Wu Yue★, Studying for master’s degree, Department of Spinal Surgery, Affiliated Hospital of Guilin Medical University, Guilin 541001, Guangxi Zhuang Autonomous Region, China jzyue305@yahoo.com.cn

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Abstract:

BACKGROUND: Establishment of animal models of tractive spinal cord injury provides a good foundation for the further investigation on pathophysiological changes and clinical significance.
OBJECTIVE: To review the construction and evaluation of tractive spinal cord injury in animal models.
METHODS: A computer-based online search of CNKI and PubMed databases was performed for related articles about animal models of tractive spinal cord injury with the key words of “tractive, spinal cord injury, animal model, neural function and motor function” in Chinese and English. Articles relevant to tractive spinal cord injury was selected. As to the same field, articles published recently or in authoritative journals were of priority. A total of 285 articles were collected in the initial search, 30 of them were retained according to the inclusion criteria.
RESULTS AND CONCLUSION: There are various kinds of spinal cord injury experimental models, including contused model, compression model, traction model, ischemia model, cutting model and chemical injury model, etc. The establishment of animal models of tractive spinal cord injury provides a good foundation for the further investigation on pathophysiological changes and clinical significance.

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