Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (47): 8919-8922.doi: 10.3969/j.issn.1673-8225.2011.47.045

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Acellular dermal matrix patch for treatment of pediatric anal fistula

Wang Li-ya, Dong Yan-qing, Zhang Peng-ju, Gong Ying-xin, Liu Feng, Niu Hui-zhong, Liu Chun-yi   

  1. Department of General Surgery, Hebei Provincial Children Hospital, Shijiazhuang  050000, Hebei Province, China
  • Received:2011-05-19 Revised:2011-06-22 Online:2011-11-19 Published:2011-11-19
  • Contact: Dong Yan-qing, Attending physician, Department of General Surgery, Hebei Provincial Children Hospital, Shijiazhuang 050000, Hebei Province, China
  • About author:Wang Ya-li★, Master, Master’s supervisor, Chief physician, Department of General Surgery, Hebei Provincial Children Hospital, Shijiazhuang 050000, Hebei Province, China ddy_rareman@ sohu.com

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Abstract:

BACKGROUND: Allogenous acellular dermal matrix patches have a good clinical effect on adult anal fistula.
OBJECTIVE: To investigate the feasibility and approach of allogenous acellular dermal matrix patches in repair of pediatric anal fistula.
METHODS: Totally 138 cases of pediatric anal fistula were randomized into two groups to receive allogenous acellular dermal matrix patch suture: group A, double-layer suture closure; group B, non-free suture.
RESULTS AND CONCLUSION: All the cases were followed for 6 months. There were no perianal swelling, abnormal appearance, induration, anal stenosis and anal shape change. After repair, some children presented with reuben from the fistula that was healed without treatment. The number of children with reuben from the fistula in group A was higher than that of group B (P < 0.01), and the appearance time was also earlier in group A (P < 0.05). Allogenous acellular dermal matrix patch has a good effect on pediatric anal fistula.

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