Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (47): 8899-8902.doi: 10.3969/j.issn.1673-8225.2011.47.040

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Biomedical materials for adhesion repair after tendon injury

Jin Dong, Zhang Guo-zhong   

  1. Department of Traditional Chinese Medicine Rehabilitation, Affiliated Hospital, Medical College of Chinese Armed Police Force, Tianjin  300162, China
  • Received:2011-06-10 Revised:2011-08-15 Online:2011-11-19 Published:2011-11-19
  • Contact: Zhang Guo-zhong, Department of Traditional Chinese Medicine Rehabilitation, Affiliated Hospital, Medical College of Chinese Armed Police Force, Tianjin 300162, China
  • About author:Jin Dong☆, Doctor, Physician, Department of Traditional Chinese Medicine Rehabilitation, Affiliated Hospital, Medical College of Chinese Armed Police Force, Tianjin 300162, China

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Abstract:

BACKGROUND: Selection of biomaterials against tendon adhesion is a hotspot in the medical field.
OBJECTIVE: To summarize the clinical application of biomaterials in adhesion repair following tendon injury.
METHODS: A computer-based search of VIP database (1999-01/2009-10) was performed for articles about biomaterials for postoperative adhesions after tendon injury. Totally 30 articles were included.
RESULTS AND CONCLUSION: Chitosan has good biological properties, which is a non-toxic, non-irritating, non-antigenic, and biodegradable biomaterial with good tissue compatibility, and it has a significant role in the prevention of tendon adhesion. Biomedical fibrin glue has a fine hematischesis and sealing function, good biocompatibility, favorable biodegradation function and a certain sterilization, which can reduce and control traumatic inflammation reactions. Numerous clinical studies and animal studies have shown that medical sodium hyaluronate, gelatin sponge, and chymotrypsin have a preventive role in postoperative tissue adhesion.

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