Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (47): 8792-8796.doi: 10.3969/j.issn.1673-8225.2011.47.013

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Adhesiveness and biocompatibility of plant adhesive

Yu Xue-song, Huang Chi-bing, Zhang Yin-fu, Fan Ming-qi, Wang Ping-xian, Feng Jia-yu, Xiao Ya   

  1. Department of Urology, Xinqiao Hospital, Third Military Medical University, Chongqing  400037, China
  • Online:2011-11-19 Published:2011-11-19
  • Contact: Huang Chi-bing, Professor, Chief physician, Department of Urology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
  • About author:Yu Xue-song☆, Studying for doctorate, Department of Urology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China yxs197994@ 163.com
  • Supported by:

    the Tackle Key Project of Chongqing City, No. csci2007AC5046*; the Funding Project during the Military Eleventh Five-year Plan, No. 2007c118*

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Abstract:

BACKGROUND: Previous studies have shown that an absorbable hemostatic adhesive with strong adhesiveness was prepared with raw materials extracted from plants.
OBJECTIVE: To detect the adhesiveness of plant adhesive on kidney and analyze its biocompatibility.
METHODS: The plant adhesive was diluted into different concentration and used on the surface of rabbit kidney. The adhesiveness in the same concentration was recorded. KM mice were divided into experimental group with the plant adhesive and control group without the plant adhesive.
RESULTS AND CONCLUSION: There were different adhesion forces with different concentrations of plant adhesive. When 0.6 mL distilled water was added to 1 g plant adhesive, the mixture had good adhesiveness. The incisions of the mice were well-healed after plant adhesive implantation, and there were no difference in blood biochemistry and immunology examinations between the experiment and control groups (P > 0.05). The histopathological staining of the experiment group did not show any inflammatory reaction in incision muscles, liver and kidney tissues. These findings indicate that the plant adhesive has good adhesiveness and biocompatibility.

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