Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (42): 7907-7910.doi: 10.3969/j.issn.1673-8225.2011.42.028

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Degradable medical films for prevention of epidural adhesion

Yang Dong-song, Zhang Shao-kun, Yan Ming, Liu Li-di   

  1. Spine Center, First Affiliated Hospital, Jilin University, Changchun  130021, Jilin Province, China
  • Received:2011-04-19 Revised:2011-05-14 Online:2011-10-15 Published:2011-10-15
  • Contact: Zhang Shao-kun, Associate professor, Master’s supervisor, Spine Center, First Affiliated Hospital, Jilin University, Changchun 130021, Jilin Province, China drzhangsk@ yahoo.com.cn
  • About author:Yang Dong-song★, Studying for master’s degree, Physician, Spine Center, First Affiliated Hospital, Jilin University, Changchun 130021, Jilin Province, China dsyang1982@163.com

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Abstract:

BACKGROUND: There are many methods for preventing epidural adhesion. Because of the unique properties, gradable medical films have a good application prospect in the future.
OBJECTIVE: To summarize the advantages, disadvantages and clinical effects of biodegradable medical films.
METHODS: A computer-based online search was performed on PuMed and CNKI databases with key words “Laminectomy, degradable medical films, epidural adhesion” in English and Chinese from January 2001 to January 2011. Repeated literatures were eliminated, and 28 articles were included.
RESULTS AND CONCLUSION: Biodegradable medical films can prevent epidural adhesion effectively, and their products can be absorbed by human body or discharged with breath and body fluids, which cannot cause harm to human body. Therefore, these films can be the ideal materials for preventing epidural adhesion. The biodegradable medical films are numerous, and experimental results are also different. Because shortcomings of a single kind of medical film, the modified film with two or more films can overcome the shortcomings, and there is a broad prospect in clinical trials in the future.

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