Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (34): 6335-6338.doi: 10.3969/j.issn.1673-8225.2011.34.016

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Preparation and bioactivity of hydroxyapatite in medical NiTi-shaped memory alloy

Yin Yan1, Ma Bao-yu1, Xia Tian-dong1, Xia Ya-yi2, Da Guo-zu3   

  1. 1State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, China
    2The Second  Affiliated Hospital of Lanzhou University, Lanzhou  730000, Gansu Province, China
    3Lanzhou Seemine Shape Memory Alloy Co., Ltd., Lanzhou  730000, Gansu Province, China
  • Received:2010-12-21 Revised:2011-01-21 Online:2011-08-20 Published:2011-08-20
  • About author:Yin Yan☆, Associate professor, State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials, Lanzhou University of Technology, Lanzhou 730050, Gansu Province, China yinyan@lut.cn
  • Supported by:

    Doctoral Fund of Lanzhou University of Technology*

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Abstract:

BACKGROUND: At present, many plasma spraying technology in titanium and its surface of alloys coated hydroxyapatite (HA) coatings, and composite materials were prepared. However, the HA coating usually desquamated during the period of cooling due to the different expansion coefficient between HA and titanium alloy substrate.
OBJECTIVE: To prepare dense, uniform coating of HA bioceramic on the surface of medical niti-shaped memory alloy, and to investigate the biocompatibility of NiTi/HA composite by animal experiment.
METHODS: HA coatings on the surface of NiTi-shaped memory alloy were prepared via electrochemical deposition from aqueous electrolytes containing calcium and phosphorus ions at low temperature and then treated with alkaline solution. The effects of technological parameter on the structure of coating were analyzed. The bioactivity of the composite materials was studied by animal implantation experiment, and compared with NiTi/HA and Ca3 (PO3)2•2H2O hybrid coating composite materials, medical NiTi-shaped memory alloy, and medical Ti alloy.
RESULTS AND CONCLUSION: The electrochemical-deposition alkali treatment is suitable to prepare bioactive ceramic coating of HA on the surface of NiTi-shaped memory alloy. Deposition voltage and temperature have strong influence on the coating structure. There were varying degrees of hyperblastosis in the surrounding region after 4 kinds of materials implanted in animal. Chondrocyte and trabecular bone formation could be seen in periosteal tissue sections. Implant materials tissue coated with HA coating had a mild reaction, the number of chondrocyte and trabecular bone was the largest in the corresponding histological section and uniform distribution. The results showed that HA coating improved the bioactivity of medical niti-shaped memory alloy.

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