Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (16): 2945-2948.doi: 10.3969/j.issn.1673-8225.2011.16.022

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Biocompatibility of artificial dura materials

Zhou Yu-feng1, Huang Mei2, Deng Cong-ying1, Tang Li-xin1   

  1. 1Department of Neurosurgery, the 324 Hospital of PLA, Jiangbei District, Chongqing  400020, China
    2Department of Out-patient, Chongqing Communication Institute, Shapingba District, Chongqing  400035, China
  • Received:2010-12-19 Revised:2011-02-10 Online:2011-04-16 Published:2013-11-11
  • About author:Zhou Yu-feng★, Master, Associate chief physician, Department of Neurosurgery, the 324 Hospital of PLA, Jiangbei District, Chongqing 400020, China zhouyufeng871@sina.com

Abstract:

BACKGROUND: Dural repair materials in the application of present research are mainly including autologous tissue repair material, allograft material, heterogeneous biological materials and synthetic materials.
OBJECTIVE: To evaluate the property and application of various repair materials in the repair of dural defects, and to find appropriate dural repair materials.
METHODS: Taking “dural, material” in Chinese as search terms, the articles related to dural defect repair materials research and a variety of materials in the clinical application of dural defect repair from CNKI database (2000-01/2010-12) were retrieved.
RESULTS AND CONCLUSION: At present autologous tissue, allograft materials, heterogeneous biological materials and synthetic materials and other dural repair materials respectively exist sources of difficulty, easy adhesion, difficult to preserve, not easily sterilized or poor biocompatibility disadvantages. Autologous tissue repair material was still the preferred material under usable circumstances, heterogeneous biological materials because of its good biocompatibility and physical and chemical properties become the most widely dural repair material in clinical application. Although heterogeneous biological materials is currently extensive use of dural repair material in clinic, because of respective inevitable shortcomings of them, dural repair material still needs further development.

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