Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (11): 1909-1912.doi: 10.3969/j.issn.1673-8225.2011.11.003

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Implanted microwave ablation of bone in vitro

Ke Jin, Yin Qing-shui, Zhang Yu, Zhang Tao, Xu Liang   

  1. Department of Orthopaedics, Guangzhou General Hospital of Guangzhou Area Command of Chinese PLA, Guangzhou  510010, Guangdong Province, China
  • Received:2010-10-21 Revised:2011-01-24 Online:2011-03-12 Published:2011-03-12
  • Contact: Yin Qing-shui, Master, Chief physician, Doctoral supervisor, Department of Orthopaedics, Guangzhou General Hospital of Guangzhou Area Command of Chinese PLA, Guangzhou 510010, Guangdong Province, China yqi@medmail.com.cn
  • About author:Ke Jin★, Studying for master’s degree, Department of Orthopaedics, Guangzhou General Hospital of Guangzhou Area Command of Chinese PLA, Guangzhou 510010, Guangdong Province, China kejin332500@yahoo.com.cn
  • Supported by:

    the Medical Scientific Research Foundation of Guangdong Province, No. B2009211*

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Abstract:

BACKGROUND: Microwave high temperature can deactivate bone tumor cells directly and maintain bone supporting effect. 
OBJECTIVE: To investigate the ablation effects of implanted microwave on bone in vitro.
METHODS: The rigid implanted microwave antenna with internally water-cooled were directly implanted into fresh procine bone in vitro. Microwave power was 60, 70, 80, 90 and 100 W, ablation duration was 300 seconds, and frequency was 2450MHz. The maximum and minimum diameter of congeal area was measured. The histomorphology and ultrastructure of congeal area specimen were observed by light microscope and electron microscope.
RESULTS AND CONCLUSION: The bone showed a reproducible lesion. The shapes of ablation lesions were elliptical in the vertical plane while rotund in the horizontal plane, maximum longitudinal and minimum longitudinal of ablation lesions were analyzed and Pathological and ultrastructural changes of the bone were observed, respectively. The ablation size enlarged with the increase of irradiation powers in differential degree. No changes can be observed in pathological. The nucleus disappeared and showed irreversible damage under electron microscope. It demonstrates that implanted microwave has ablation effects on bone in vitro.

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