Abstract:

BACKGROUND: Besides allogeneic skin, porcine skin, buckskin, autoallergic eschar, or vaseline gauze are used as microskin coverings, especially the porcine skin, which is extensive used due to similar to human skin structures and low costs. 
OBJECTIVE: To observe the clinical effects of acellular porcine skin to cover auto-microskin on extensive deep burns.
METHODS: Fifteen cases with extensive deep burns were treated with removal of eschar at the early stage or granulation tissue debridement, transplantation of auto-microskin covered with acellular porcine skin. The rejection of acellular porcine skin, the survival of the microskin grafts and wound repair of skin were observed and retrospectively analyzed postoperatively.
RESULTS AND CONLUSION: The acellular porcine skin could suck intact in the wound postoperatively. And it turned to cinnamomeous or purple black and a dry scab within 5-7 post-operation days, a small amount of exudate was found under covering occasionally, and the acellular porcine skin did not become soft and was not stripped after fenestration and drainage. The porcine skin gradually separated from the auto-microskin during 3-4 weeks post-operation. The wound completely healed, and the appearance and elasticity of skin recovered to some extent, and scars were inconspicuous. The results showed that it is reliable to use acellular porcine skin as a substitute of alloskin to cover auto-microskin in the treatment of extensive deep burns, and the wound is ideally repaired.