Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (5): 823-826.doi: 10.3969/j.issn.1673-8225.2011.05.015

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Chronic rejection following liver transplantation in one case 

Yang Li-min, Wang Shou-yun, Yan Chun-wei, Chen Han-dong   

  1. Department of Hepatopathy, Third Hospital of Qinhuangdao, Qinghuangdao  066000, Hebei Province, China
  • Received:2010-08-12 Revised:2010-10-19 Online:2011-01-29 Published:2011-01-29
  • About author:Yang Li-min★, Master, Associate chief physician, Department of Hepatopathy, Third Hospital of Qinhuangdao, Qinghuangdao 066000, Hebei Province, China lantianq68@163.com

Abstract:

BACKGROUND: Chronic rejection develops slowly with concealed occurrence, presented with nonreversible liver function subsidence or loss, which can not be treated effectively.
OBJECTIVE: To analyze a liver transplant recipient with chronic rejection in order to provide reference accurate diagnosis at an early time.
METHODS: The process of three-time admission of a liver transplant recipient with chronic rejection was analyzed. Type-B ultrasonic showed: ①Echo of liver parenchyma was heightened, thickened, and inequable. ②After cholecystectomy.
③Splenomegaly. ④Abdominal dropsy. Abdominal CT showed: ①After liver transplantation. ②Splenomegaly. Liver-protecting, support and symptomatic therapy were performed in duration of hospital stay, but the alanine transaminase and aspartic transaminase levels did not decreased, total bilirubin level increase, with repetitive abdominal infections. Depleting other liver damage reasons, the recipient was confirmed suffering from chronic rejection.
RESULTS AND CONCLUSION: Chronic rejection-induced liver damage should be aroused attention and diagnosed when the recipient suffering unexplained damages. Histopathologic examination contributes to the diagnosis of chronic rejection after depleting other liver damage reasons.

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