Development and efficacy of a bio-feedback artificial anal sphincter perception system

doi:10.3969/j.issn.2095-4344.2013.05.020

Abstract

Abstract:

BACKGROUND: Artificial anal sphincter is a new way to treat fecal incontinence. However, present artificial anal sphincter lacks of awareness and feedback function, and patients can control their defecation mainly through their habits rather than the existence of the intestinal contents. Research into an awareness and feedback system is the primary issue in the development of artificial anal sphincter.
OBJECTIVE: To develop a bio-feedback artificial anal sphincter perception system which could perceive and feedback the change in intestinal pressure and the volume of intestinal contents.
METHODS: Twenty healthy New Zealand rabbits were used to test its feasibility, and the experiments were performed on the distal part of proximal colon of the rabbits. The pressure of intestinal canal and pressure sensing cuff were measured after injecting four simulated intestinal contents, including gas, liquid, semi-fluid and solid into the intestinal canal respectively. The relationship between the volume of the four states of intestinal contents and the intestinal canal pressure and the cuff pressure was analyzed.
RESULTS AND CONCLUSION: The results of the experiment showed that the pressure of intestinal canal and pressure sensing cuff was increased with the increasing of the volume of intestinal contents, and the pressure and the volume was positively correlated within a certain range. According to the experiment, the bio-feedback artificial anal sphincter perception system could effectively reflect the change of intestinal pressure and the volume of intestinal contents, and may be an effective strategy to address the awareness and feedback problem of artificial anal sphincter, thereby laying the basis for the research of intelligent bio-feedback artificial anal sphincter.

Key words: organ transplantation, transplantation and immunology, fecal incontinence, artificial anal sphincter, pressure sensing cuff, pressure sensor, bio-feedback, intelligent artificial anus, intestinal contents, intestinal canal pressure, tissue construction, tissue engineering, provincial grants-supported paper, photographs- containing paper of organ transplantation

CLC Number:

R318

Xiao Zhong, Huang Zong-hai, Shi Fu-jun, Chen Fei, Guo Xiong-bo, Lin Xiao-hua. Development and efficacy of a bio-feedback artificial anal sphincter perception system[J]. Chinese Journal of Tissue Engineering Research, 2013, 17(5): 894-901.

Figures/Tables 3

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