Abstract:

 Lung transplantation is the only effective treatment for final stage pneumonopathy. However, bronchitis obliterans, as the main of complication, can prevent the long term survival after lung transplantation. Tracheal epithelium cell is the main target organ of the tardive reject reaction. This paper briefly explains the immunologic mechanism regarding the development of bronchitis obliterans, and the role of tracheal epithelium cell in the study, with aim of exploring the initial relationship between tracheal epithelium cell and bronchitis obliterans, and to find a method to solve the long-term survival of lung transplantation.