Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (16): 2425-2432.doi: 10.3969/j.issn.2095-4344.2016.16.020

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Biomechanical properties of the lumbosacral spine and application of internal fixation materials

Sun Hong-hao1, Guo Qing-sheng2, Zhu Zhi-yong3   

  1. 1Third Department of Clinical Medicine, China Medical University, Shenyang 110033, Liaoning Province, China; 2Second Department of Orthopedics, 3Third Department of Orthopedics, the People’s Hospital of Liaoning Province, Shenyang 110016, Liaoning Province, China
  • Received:2016-02-16 Online:2016-04-15 Published:2016-04-15
  • About author:Sun Hong-hao, Third Department of Clinical Medicine, China Medical University, Shenyang 110033, Liaoning Province, China
  • Supported by:

    the Natural Science Foundation of Liaoning Science and Technology Department, No. 201102104

Abstract:

BACKGROUND: In recent years, the spinal internal fixation technology has made rapid development based on biomechanics and material sciences.

OBJECTIVE: To review the biomechanical characteristics of the lumbosacral spine and the application of various internal fixation materials in the reconstruction of spinal stability after lumbosacral spinal tuberculosis.
METHODS: A computer-based search of Medline and Chinese Journal Full-Text Database was performed for relevant articles using the keyword of “lumbosacral spinal tuberculosis, biomaterials materials, fixation” in English and Chinese, respectively.
RESULTS AND CONCLUSION: Rigid internal fixation is a conventional treatment for lumbosacral tuberculosis, which improves the spinal alignment and stability during the spinal reconstruction. Metallic materials such as stainless steel, titanium and titanium alloys have been widely used in rigid internal fixation, but metal sedimentation, non-transparency, stress shielding and osteoporosis after internal fixation impact the fusion effects and imaging observation. Absorbable materials as newly-developing materials have good biocompatibility and biodegradability in orthopedic internal fixation. To select the appropriate material for internal fixation, the biomechanical properties of internal fixation materials will be investigated according to the degree of vertebral damage and lumbosacral stability.  
中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程

Key words: Internal Fixators, Spine, Biomechanics, Tissue Engineering