Seed cells and scaffold materials for construction of tissue-engineered tendon to repair exercise-induced tendon injury

doi:10.3969/j.issn.2095-4344.2015.51.024

Abstract

Abstract:

BACKGROUND: To harvest a large amount of seed cells with regenerative viability and ideal scaffold materials with mechanical properties similar to the human tendon is crucial for current tissue-engineered tendon research.
OBJECTIVE: To summarize and analyze the progress in seed cells and scaffold materials for tissue-engineered tendon.
METHODS: Literatures addressing tendon tissue engineering published in recent years were retrieved and combined with latest achievements to analyze the research progress in seed cell sources, ideal scaffold materials, and histocompatibility for tendon tissue engineering.
RESULTS AND CONCLUSION: Commonly used seed cells for tendon tissue engineering include mesenchymal stem cells, tendon stem cells and embryonic stem cells, all of which are ideal cells that can differentiate to bone, cartilage and fat so as to repair damaged tendons. Tendon tissue engineering scaffolds are made of natural materials and synthetic materials, which should have good biocompatibility and appropriate mechanical properties. In the future, composite materials will be the research focus of tendon tissue engineering scaffold materials.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

CLC Number:

R318

Yang Jian, Ge Jian-zhong. Seed cells and scaffold materials for construction of tissue-engineered tendon to repair exercise-induced tendon injury[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(51): 8333-8337.

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