Continuous aspirin anticoagulation affects blood loss during total knee and hip arthroplasties

doi:10.3969/j.issn.2095-4344.2015.26.010

Abstract

Abstract:

BACKGROUND: Many patients underwent aspirin anticoagulation in preventing cardiovascular disease before hip and knee replacement. No report addressed the effect of aspirin on blood loss during perioperative stage in patients receiving hip and knee replacement.
OBJECTIVE: To observe the effect of perioperative continuous low-dose aspirin anticoagulation application on total hip arthroplasty or total knee arthroplasty.
METHODS: A total of 40 patients with primary total hip arthroplasty or total knee arthroplasty were enrolled in the Department of Orthopedics, Tianjin First Center Hospital from December 2012 to August 2013. According to anticoagulation scheme, they were divided into two groups (n=20). In the observation group, 100 mg/d aspirin anticoagulation was continuously used before replacement for a long period, and the medicine was not withdrawn except the day of replacement. In the control group, aspirin anticoagulation was not used, and their ages were similar to the observation group. The operation was conducted by the same physician in the observation and control groups. 10 patients received total hip arthroplasty and 10 patients received total knee arthroplasty in both
groups. Bleeding was stopped actively during replacement. After replacement, pressurized ice compress was used to reduce bleeding. At 48 hours after replacement, wound drainage, perioperative hemoglobin and the incidence of complications were recorded. Joint function recovery was observed at 3 months of follow-up.
RESULTS AND CONCLUSION: Hemoglobin levels before and after operation, postoperative blood drainage at 48 hours, perioperative hemoglobin changes, the incidence of complication, and joint function score at 3-month follow-up did not show significant difference between both groups. These findings indicate that it is safe to use some measures for reducing blood loss and continue low-dose aspirin in the perioperative period. The use of aspirin did not impact blood loss.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip, Aspirin, Anticoagulants

CLC Number:

R318

You Jia, Fan Meng, Jiang Wen-xue. Continuous aspirin anticoagulation affects blood loss during total knee and hip arthroplasties [J]. Chinese Journal of Tissue Engineering Research, 2015, 19(26): 4149-4152.

Figures/Tables 3

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