Chinese Journal of Tissue Engineering Research

Previous Articles    

Finite Element Analysis of An Acute Cerebral Embolism Example of Mechanical Embolectomy Using Penumbra System

Liu Bo1, Xie Peng2, Li Zhi-wei1   

  1. 1Department of Neurology,YongChuan Hospital,Chongqing Medical University,Chongqing 402160,China；2Department of Neurology, The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China
  • Received:2013-08-07 Online:2014-04-30 Published:2014-04-30
  • Contact: Central Hospital of Xiangyang, Xiangyang 441g, Xiangyang 441021, Hubei Province, China liankai2000@163.com
  • Supported by:

    Natural Science Foundation of Yongchuan District of Chongqing City, No. Ycstc,2013nc8031; Foundation of Chongqing Municipal Health Bureau, No. 2010-2-250;Soft Science Foundation of Yongchuan District of Chongqing City, No. Ycstc, 2011BE5004

PDF

675

Abstract:

BACKGROUND: Cerebral embolism is a common disease with high mortality, mechanical thrombectomy using Penumbra system is considered to be a new and effective method. However, there were few cases currently, it is a unclear understanding of effects on regional cerebral blood vessels using this kind of surgery.

OBJECTIVE: Numerical simulation describes effects on regional cerebral blood vessels of an acute cerebral embolism patient by mechanical embolectomy using Penumbra system.
METHODS: A 77-year-old woman was selected suffering from the left middle cerebral artery embolization. Various raw data was collected in emergency cerebral angiography,then mechanical thrombectomy using Penumbra system was carried out successfully.After these raw data was processed into dimensional numerical models of two kinds of embolectomy methods ( " suction bolt method from near to far " and " suction bolt method from far to near " ), then finite element analysis was carried out.
RESULTS: Successfully complete modeling and finite element analysis . The results suggest that:compared with " suction bolt method from near to far ", " suction bolt method from far to near " models had smaller velocity of flow in catheter and smaller wall shear stress of thrombus (P <0.01), and had larger wall shear stress of blood vessel wall, deformation of blood vessel wall (P <0.01) and deformation of thrombus (P < 0.05).

CONCLUSIONS: Finite element analysis of mechanical embolectomy using Penumbra system can help physicians involved in a clearer understanding of their impact on cerebrovascular of patients. As a research method,It is worth to continue to explore in the future.

CLC Number: