Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (19): 3568-3575.doi: 10.3969/j.issn.1673-8225.2012.19.030

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Stem cells in the treatment of spinal cord injury 

Chen Xiao-chun1, Zhang Yang1, Li Zhi1, Zhou Li-nan2   

  1. 1Department of Orthopaedics, Fengtian Hospital of Shenyang Medical College, Shenyang  110024, Liaoning Province, China; 2Teaching Laboratory of Morphology, Occupation and Technology College of Liaoning Province,  Shenyang 110010, Liaoning Province, China
  • Received:2012-02-09 Revised:2012-04-14 Online:2012-05-06 Published:2012-05-06
  • About author:Chen Xiao-chun★, Master, Associate chief physician, Department of Orthopaedics, Fengtian Hospital of Shenyang Medical College, Shenyang 110024, Liaoning Province, China chenxiaochun2012@sina.com

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Abstract:

BACKGROUND: Spinal cord injury is a serious trauma to central nervous system. Tissue engineered-cell transplantation provides a new approach for spinal cord injury.
OBJECTIVE: To multivariately analyze the literature on neural stem cells transplantation for the treatment of spinal cord injury through Scopus database.
DESIGN: Bibliometric analysis.
DATA RETRIEVAL: A retrieval was performed for the literature of stem cells transplantation for treating spinal cord injury during 2006-01 and 2011-12 in Scopus. The retrieval results were analyzed, and the trends were described in words and graphics.
SELECTIVE CRITERIA: Articles on stem cells transplantation for the treatment of spinal cord injury include the following types:  (1) peer-reviewed original paper; (2) reviews; (3) meeting notes and abstracts; (4) proceeding papers; (5) editorial materials; (6) letters. Exclusive criteria: (1) Articles unrelated the study of stem cells transplantation for the treatment of spinal cord injury. (2) Articles published before 2006. (3) Articles were not published on journals. (4) Articles which need to be retrieved by phone.
MAIN OUTCOME MEASUREMENTS: Type of document, authors, publication year, journal distribution, discipline distribution, institutional information, citation frequency and country distribution.
RESULTS: A total of 1 080 literatures on stem cells transplantation for the treatment of spinal cord injury were retrieved in Scopus database, in which most of papers were published as original articles (n=607). Fifteen articles were identified as classic literatures. The overall number of literature had an upward trend from 2006 to 2011, and the articles with high citations were published in Journal of Neuroscience. Currently, United States published most literatures, accounting for 28.5% of all the literatures. The second is China, which published 212 literatures, accounting for 19.6% of all the published literatures. 
CONCLUSION: This paper provides a valuable reference for researchers to understand the overview and present situation of this field. 

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