Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (17): 3130-3133.doi: 10.3969/j.issn.1673-8225.2012.17.021

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Meta analysis of reamed versus non-reamed intramedullary nailing for closed tibial fractures in adults 

Wang Lei1, Chen Gen-yuan1, Wang Feng-feng2, He Yu-ping3, Wang Tao3   

  1. 1Department of Orthopedics, First Clinical Medical College of Lanzhou University, Lanzhou 730000, Gansu Province, China; 2Department of Orthopedics, Xi’an Chang’an Hospital, Xi’an  710016, Shaanxi Province, China; 3Second Clinical Medical College of Lanzhou University, Lanzhou  730000, Gansu Province, China
  • Received:2011-09-29 Revised:2011-11-05 Online:2012-04-22 Published:2012-04-22
  • Contact: Chen Gen-yuan, Professor, Department of Orthopedics, First Clinical Medical College of Lanzhou University, Lanzhou 730000, Gansu Province, China chengenyuan2009@163.com
  • About author:Wang Lei★, Studying for master’s degree, Department of Orthopedics, First Clinical Medical College of Lanzhou University, Lanzhou 730000, Gansu Province, China wangleizhuimeng@163.com

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Abstract:

BACKGROUND: Some control studies attempt to answer the advantages and disadvantages of the issue on reamed and non-reamed intramedullary nailing for closed tibial fractures, but the conclusions are different.
OBJECTIVE: To determine the efficiency and safety of reamed versus non-reamed intramedullary nailing for closed tibial fractures in adults by Meta analysis.
METHODS: PubMed, Embase, Cochranel Library, CBMdisc, Weipu information database and Wanfang were searched by computer. Randomized controlled trials related to reamed versus non-reamed intramedulary nailing for closed tibial fractures in adults were included. The quality of trials was critically assessed. RevMan 5.0 software was used for data analysis．
RESULTS AND CONCLUSION: Three randomized controlled trials were included. Meta analysis showed that compared with the non-reamed intramedulary nailing for closed tibial fractures in adults, the nonunion rate decreased [RR 0.25, 95%CI(0.08, 0.79), P=0.02] and implant failure rate decreased significantly [RR 0.25, 95%CI(0.12, 0.52) P=0.000 2] in the reamed intramedullary nailing for closed tibial fractures in adults. Compared with non-reamed intramedulary nailing for closed tibial fractures in adults, reamed intramedulary nailing decreases the nonunion rate and implant failure are rare. There is no statistical difference in the rate of delayed fracture healing, malunion rate and the incidence of compartment syndrome.

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