Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (13): 2362-2365.doi: 10.3969/j.issn.1673-8225.2012.13.019

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Effect of plaster external fixation on the histomorphological changes for bone-tendon junction healing

Wang Jing1, Zhang Chao-yue2, Tan Cai-Fu3   

  1. 1Department of Orthopedics, Hunan Provincial People’s Hospital, Changsha  410005, Hunan Province, China; 2Department of Orthopedics, the Third Xiangya Hospital of Central South University, Changsha  410013, Hunan Province, China; 3Deprtment of Orthopedics, Zhuzhou TCM Traumatic Hospital, Zhuzhou  412007, Hunan Province, China
  • Received:2011-12-09 Revised:2012-02-01 Online:2012-03-25 Published:2012-03-25
  • Contact: author: Zhang Chao-yue, Professor, Doctoral supervisor, Department of Orthopedics, the Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China zcy1958@medmail.com
  • About author:Wang Jing★, Master, Attending physician, Department of Orthopedics, Hunan Provincial People’s Hospital, Changsha 410005, Hunan Province, China wjzj930@yahoo.com.cn

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Abstract:

BACKGROUND: Plaster external fixation has a positive effect on bone-tendon junction healing, but there is no in-depth study on the repair mechanism.
OBJECTIVE: To investigate the effect of plaster external fixation on the histomorphological changes for bone-tendon junction healing.
METHODS: The bone-tendon junction healing models were established by cutting off the junction between the patellar tip and the patellar tendon as well as the distal part of the patella. The models were divided into experimental group and model group. The models in the experimental group were performed with plaster external fixation and those in the model group were without fixation. Each group got the sample at 2, 4 and 8 weeks after operation.
RESULTS AND CONCLUSION: Hematoxylin-eosin staining, Safranin’O staining, macrophages immunohistochemistry staining and integral absorbance showed that the tissue edema and adhesion at the bone-tendon junction in the experimental group were better than those in the model group, cartilage cells and bone tissue formation and differentiation in the experimental group were significantly better those those in the model group, and degree of the inflammation in the experimental group was light and disappeared quickly. External fixation can accelerate the process of bone-tendon repair and promote the healing. 
 

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