Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (51): 9671-9674.doi: 10.3969/j.issn.1673-8225.2011.51.041

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Advances in various biomaterials for hemostasis and clinical application of compound materials for hemostasis

Li Xue-jun, Sun Yuan-yuan   

  1. Department of Hematology, First Hospital of Liaoning Medical University, Jinzhou  121001, Liaoning Province, China
  • Received:2011-10-05 Revised:2011-11-03 Online:2011-12-17 Published:2011-12-17
  • Contact: Sun Yuan-yuan, Master, Department of Hematology, First Hospital of Liaoning Medical University, Jinzhou 121001, Liaoning Province, China lxs7205@163.com
  • About author:Li Xue-jun, Department of Hematology, First Hospital of Liaoning Medical University, Jinzhou 121001, Liaoning Province, China

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Abstract:

BACKGROUND: With development of biomedical polymers, such as cellulose, chitin, polyvinyl alcohol and collagen, the application of materials for hemostasis has advanced.
OBJECTIVE: To summarize advances in dressing materials for hemostasis and evaluate their clinical values.
METHODS: A computer-based online search of Wanfang and PubMed database was performed for articles regarding medical polymer dressing materials for hemostasis published between January 1996 and December 2010 with key words “materials for hemostasis, fibrin, polymers, collagen, gelatin sponge” in Chinese or “biological; occlude the flow of blood; gelatin sponge; fibrae sanguis”. Articles published recently in authoritative journals of the same domain were selected. 126 articles were collected, and 28 were included for review analysis.
RESULTS AND CONCLUSION: In recently, absorbable materials for hemostasis, including chitosan, fibrin glue, absorbable gelatin sponge, microfiber collagen, alginate and hydrocolloid. Different materials have various mechanisms and hemostasis effects. Comparisons in the effects of various compound materials for hemostasis showed that the pathways and mechanisms of different materials for hemostasis require further investigation to develop more effective and convenient materials for hemostasis.

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