Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (48): 9011-9014.doi: 10.3969/j.issn.1673-8225.2011.48.020

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Preliminary study of intelligent artificial intestinal content sensory nerve

Li Jian-guo1, Shi Fu-jun1, Xu Shuai1, Chen Fei1, Huang Zong-hai1, Zheng Xi-jun2   

  1. 1Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou  510282, Guangdong Province, China
    2National Science Park of South China University of Technology, Guangzhou  510640, Guangdong Province, China
  • Received:2011-08-04 Revised:2011-09-09 Online:2011-11-26 Published:2011-11-26
  • Contact: Huang Zong-hai, Doctor, Chief physician, Professor, Doctoral supervisor, Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China drhuangzh@yahoo.com.cn
  • About author:Li Jian-guo☆, Studying for doctorate, Attending physician, Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China lijianguo0420@163.com
  • Supported by:

    the Science and Technology Plan Foundation of Guangdong Province, No. 2009A030200014*

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Abstract:

BACKGROUND: Present artificial anal sphincter lacks awareness of the stool, and patients control their defecation mainly through their habits rather than the existence of the stool in the gut.
OBJECTIVE: To research whether artificial intestinal content sensory nerve could distinguish different status of intestinal contents, so as to lay the basis for the research and development of intelligent artificial anal sphincter (IAAS).
METHODS: Twenty healthy New Zealand rabbits were used, and the experiments were performed on the distal part of proximal colon of the rabbits. Five positions were randomly chosen on each proximal colon as the measuring points, and an intelligent artificial intestinal content sensory nerve was used to judge the solid, liquid, gaseous, and vacant status of the contents inside the colon lumen.
RESULTS AND CONCLUSION: The rate of the right judgment about the solid, liquid, gaseous, and vacant status of the contents were 96%, 99%, 100%, 100% respectively. This “intelligent artificial intestinal content sensory nerve” could be used to judge whether or not the feces exists and to distinguish various status of contents inside the intestinal lumen. Using ultrasound to detect the information of different status of intestinal lumen may be an effective method.

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