Abstract:

BACKGROUND: Anterior cruciate ligament injury is extremely difficult for athletes to fully recover, and can shorten the exercise span.
OBJECTIVE: To summarize the recent research progress on the application of tissue-engineered anterior cruciate ligament in repair of exercise injury.
METHODS: An online search of VIP database and PubMed database was performed for relevant articles published between January 1994 and December 2010. A total of 28 articles on sports-related anterior cruciate ligament injury and tissue-engineered ligament were retrieved. The discussion was mainly focused on the recent development of tissue-engineered anterior cruciate ligament reconstruction, the sources of anterior cruciate ligament seed cells, the application of cytokine in reconstruction of anterior cruciate ligament and the basic research on tissue-engineered anterior cruciate ligament.
RESULTS AND CONCLUSION: Autohealing ability of sports-related anterior cruciate ligament is extremely poor, so it is extremely difficult for athletes to recover. In recent years, research on tissue-engineered anterior cruciate ligament has made rapid progress with prospect and extensive application. But with regard to application, the optimal clinical outcomes of anterior cruciate ligament repair and reconstruction can only be achieved by organically blending the selection of tissue-engineered seed cells, the construction of scaffold materials with the basic research on tissue-engineered anterior cruciate ligament, as well as using growth factor properly.