Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (36): 6817-6820.doi: 10.3969/j.issn.1673-8225.2011.36.039

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The research of periodontal ligament stem cells

Zhang Ying, Song Li   

  1. Second Affiliated Hospital of Nanchang University, Nanchang  330006, Jiangxi Province, China
  • Received:2011-03-12 Revised:2011-05-02 Online:2011-09-03 Published:2011-09-03
  • Contact: Song Li, Department of Stomatology, Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China songli200200@hotmail.com
  • About author:Zhang Ying★, Master, Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China

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Abstract:

BACKGROUND: Periodontal ligament stem cells isolated from periodontal ligament tissue is considered to be the preferred seed cells with self-renewal ability in periodontal tissue engineering and can differentiate to form three kinds of periodontal tissues: alveolar bone, periodontal ligament and cementum.
OBJECTIVE: To review the articles about isolation, identification, and relevant factors of periodontal ligament stem cells in recent years.
METHODS: The first author searched PubMed databases and CKNI database (2004-01/2010-09) for articles regarding isolation, identification, and relevant factors of periodontal ligament stem cells using the keywords of “periodontal ligament stem cells” in English and “periodontal ligament, stem cells” in Chinese. Repetitive articles were excluded, and finally, 35 articles were included.
RESULTS AND CONCLUSION: Periodontal ligament stem cells are a kind of potential seed cells for periodontal tissue engineering, which can reconstruct tissue-engineered periodontal ligament and improve the healing of periodontal defects. Biological properties of periodontal ligament stem cells have been gradually found and their research remains to be further improved.

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