Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (48): 7245-7250.doi: 10.3969/j.issn.2095-4344.2016.48.015

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Lumbosacral sagittal parameters measured by magnetic resonance in association to L5/S1 intervertebral disc degeneration

Ding Mu-chen1, Shi Zhi-cai1, Lu Chun-wen1, Wu Jin-hui1, Wang Chao1, Yuan Jia-bin1, Zhou Zhen2   

  1. 1Department of Orthopedics, 2Department of Imaging, Changhai Hospital Affiliated to The Second Military Medical University, Shanghai 200433, China
  • Revised:2016-10-15 Online:2016-11-25 Published:2016-11-25
  • Contact: Shi Zhi-cai, M.D., Chief physician, Department of Orthopedics, Changhai Hospital Affiliated to The Second Military Medical University, Shanghai 200433, China
  • About author:Ding Mu-chen, Studying for master’s degree, Physician, Department of Orthopedics, Changhai Hospital Affiliated to The Second Military Medical University, Shanghai 200433, China
  • Supported by:

    the National Natural Science Foundation of China, No. 81272026, 81672204

Abstract:

BACKGROUND: Many studies have investigated the relationship between lumbosacral sagittal parameters and the disc degeneration diseases. However, the objects of these studies were mainly the patients with disc herniation, and parameters were measured on CT or X-ray. There are few publications reporting the relationship between lumbosacral sagittal parameters, which were measured on MRI, and patients who underwent surgery with disc extrusion.

OBJECTIVE: To measure and compare the lumbosacral sagittal parameters in L5/S1 disc extrusion patients, and to investigate the relationship between the lumbosacral sagittal parameters and L5/S1 disc degeneration diseases.
METHODS: A total of 90 lumbago patients aged 18 to 35 years old were included from the Department of Orthopedics, Changhai Hospital Affiliated to The Second Military Medical University from September 2014 to April 2016 for retrospective analysis. According to with or without L5/S1 intervertebral disc protrusion, they were divided into intervertebral disc herniation group (69 cases) and disc extrusion group (21 cases received surgery). The intervertebral disc herniation group was subdivided into degeneration group (35 cases) and control group (34 cases) according to with or without L5/S1 degeneration. Angles of lumbar lordosis (LL), sacral table angle (STA) and lumbosacral angle (LSA) were measured. 
RESULTS AND CONCLUSION: Compared to the control group, the difference of LL was not significant in the degeneration group (P > 0.05), but STA and LSA were significantly reduced (P < 0.05). Compared with the no-disc herniation group, LL, STA and LSA were all decreased significantly in the disc extrusion group (P < 0.05). These results confirmed that LL in young adults with disc extrusion decreased significantly, however, in patients with disc degeneration, the decrease was not significant. The decrease in STA and LSA was strongly associated with disc degeneration diseases. STA and LSA are important parameters in the clinical evaluation of lumbosacral sagittal balance. 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Tissue Engineering, Intervertebral Disk, Biomechanics

CLC Number: