Influential factors for hidden blood loss after primary unilateral total knee arthroplasty

doi:10.3969/j.issn.2095-4344.2016.26.004

Abstract

Abstract:

BACKGROUND: Hidden blood loss is one of most important complications after total knee arthroplasty, but the mechanism and influential factors are not yet clear.

OBJECTIVE: To analyze the relative influential factors for hidden blood loss in primary unilateral total knee arthroplasty.

METHODS: Data of 235 patients who had undergone primary unilateral total knee arthroplasty from April to September 2014 were retrospectively studied. There were 38 males and 197 females aged from 48 to 82 years old with a mean age of 66 years. The Gross formula was used to calculate the amount of hidden blood loss. The effects of gender, age, height, body weight, body mass index, anesthesia method, administration of tranexamic acid, postoperative anticoagulation method, type of prosthesis, tourniquet time and pre-operative coagulation function on the postoperative hidden blood loss and total blood loss after total knee arthroplasty were analyzed.

RESULTS AND CONCLUSION: (1) Significant differences in hidden blood loss and total blood loss after total knee arthroplasty were detected between male and female patients (P < 0.01). Significant differences in hidden blood loss and total blood loss were found between tranexamic acid and non-tranexamic acid groups (P < 0.05, P < 0.01). (2) Multivariate linear regression analysis showed that preoperative hemoglobin level and height were important factors influencing the blood loss after arthroplasty. Hidden blood loss and total blood loss were not correlated with age, body mass index, anesthesia method, postoperative anticoagulation method, type of prosthesis, tourniquet time and preoperative coagulation function. (3) Results indicate that gender and administration of tranexamic acid affect hidden blood loss and total blood loss after total knee arthroplasty. However, age, body mass index, anesthesia method, postoperative anticoagulation method, type of prosthesis, tourniquet time and preoperative coagulation function do not greatly affect hidden blood loss.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Arthroplasty, Replacement, Knee, Blood Loss, Surgical, Prosthesis Implantation, Tissue Engineering

CLC Number:

R318

Huang Jia-gu, Zhang Ke, Tian Hua, Wang Xiao-yong, Cai Hong, Li Zi-jian, Li Feng. Influential factors for hidden blood loss after primary unilateral total knee arthroplasty[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(26): 3823-3829.

Figures/Tables 2

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