Artificial bone or autologous bone grafting combined with pedicle screw fixation for repair of spinal tuberculosis

doi:10.3969/j.issn.2095-4344.2015.52.024

Abstract

Abstract:

BACKGROUND: With the development of fixation materials and technology, scholars began to use artificial bone materials combined with pedicle screw fixation in the repair of spinal tuberculosis.

OBJECTIVE: To summarize the characteristics of artificial bone materials combined with pedicle screw fixation in the repair of spinal tuberculosis.

METHODS: The literatures about artificial bone graft materials in repair of spinal tuberculosis were retrieved from CNKI and PubMed database during 1985 to 2014 by computer. The keywords were “spinal tuberculosis, bone transplantation, internal fixation” in Chinese and English, respectively.

RESULTS AND CONCLUSION: In the repair of spinal tuberculosis using artificial bone materials combined with pedicle screw fixation, autologous bone is the gold standard for bone grafting, presenting with no immune rejection. To avoid the occurrence of limited bone mass, pain and other complications, however, artificial bone materials have been extensively studied. Currently used artificial materials mainly include titanium and its alloys, hydroxyapatite composites and medical calcium sulfate, which all have good biocompatibility. But there are still certain limitations and shortcomings.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

CLC Number:

R318

Jiang Peng-fei, Zhai Wen-bin. Artificial bone or autologous bone grafting combined with pedicle screw fixation for repair of spinal tuberculosis[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(52): 8498-8502.

References

[1] Kumar R.Spinal tuberculosis: with reference to the children of northern India.Childs Nerv Syst.2005;21(1):19-26.

[2] Khoo LT,Mikawa K,Fessler RG.A surgical revisitation of Pott distemper of the spine. Spine J.2003;3(2):130-145.

[3] 胥少汀.实用骨科学[M].4版.北京:人民军医出版社,2012.

[4] Moon MS.Tuberculosis of the spine controversies and a challenge.Spine (Phila Pa 1976)1997;22(20):1791-1797．

[5] Dickman CA,Rosenthal D,Karahalios DG,et al.Thoracic vertebrectomy and reconstruction using a microsurgical thoracoscopic approach.Neurosurgery.1996;38(2):279-293.

[6] Nene A,Bhojraj S.Results of nonsurgical treatment of thoracic spinal tuberculosis in adults.Spine J.2005;5(1):79-84.

[7] 张少华.应用异体骨移植前路病灶清除内固定治疗胸腰椎结核[J].内蒙古医学杂志,2010, 42(6):739-741.

[8] 张泽华,许建中,谭祖键,等.改良前方入路结核病灶清除、同种异体骨移植、内固定治疗颈胸段脊柱结核[J].中国脊柱脊髓杂志, 2006,16(1):41-44.

[9] 李小军,王文礼,刘海波.椎弓根钉系统固定结合经椎弓根自体骨移植治疗胸腰椎爆裂性骨折疗效分析[J].四川医学, 2012, 33(9): 1597-1599.

[10] 罗鹏,李志刚,张勇,等.前路一期病灶清除椎间植骨前路内固定治疗胸腰椎结核54例[J].实用医学杂志,2011,27(22):4100-4102．

[11] 陈水连,李森,柯宝毅,等.下腰椎结核侧后方入路病灶清除内固定在临床中的应用[J].中国当代医药,2014,19(10):59-60.

[12] Rajasekaran S, Soundarapandian S.Progression of kyphosis in tuberculosis of the spine treated by anterior arthrodesis.J Bone Joint Surg Am.1989;71(9):1314-1323.

[13] Wawro W,Konrad L,Aebi M.Single segment ingment internal fixator device in treatment of thoracolumbar vertebral fractures. Unfallchirurg.1994;97(3):114-120.

[14] Cavusoglu H,Kaya RA,Turkmenoglu ON,et al.A long-termfollow-up study of anterior tibial allografting and instrumentation in the management of thoracolumbar tuberculous spondylitis.J Neurosurg Spine.2008;8(1):30-38.

[15] Nakamura H,Matsuda H,Konishi S,et al.Single stage excisiong of hemivertebrae via the posterior approach alone for congenital spine deformity.Spine (Phila Pa 1976).2002; 27(1):110-115.

[16] Lee TC,Lu K,Yang LC,et al.Transpedicular instrumentation as an adjunct in the treatment of thoracolumbar and lumbar spine tuberculosis with early stage bone destruction.J Neurosurg.1999;9(spine 2):163-169.

[17] Karaeminogullari O,Aydinli U,Ozerdemoglu R, et al.Tuberculosis of the lumbar spine: Outcomes after combined treatment of two-drug therapy and surgery. Orthopedics.2007; 30(1):55–59.

[18] Ozdemir HM,Us AK,O?ün T.The role of anterior spinal instrumentation and allograft fibula for the treatment of pott disease.Spine (Phila Pa 1976).2003;28(5):474–479.

[19] Benli IT,Acaro?lu E,Akalin S,et al.Anterior radical debridement and anterior instrumentation in tuberculosis spondylitis.Eur Spine J.2003;12(2):224–234.

[20] Kim KS,Ko SH,Youm KS,et al.Anterior spinal instrumentation in treatment of spinal tuberculosis.J Kor Orthop Assoc. 1998; 33:1560–1568.

[21] Bezer M,Kucukdurmaz F,Aydin N,et al.Tuberculous spondylitis of the lumbosacral region: long-term follow-up of patients treated by chemotherapy, transpedicular drainage, posterior instrumentation, and fusion.J Spinal Disord Tech. 2005;18(5): 425-429.

[22] 金大地,陈建庭,张浩,等.一期前路椎体间植骨并内固定治疗胸腰椎结核[J].中华外科杂志,2000,24(12):900-902．

[23] Oga M,Arizono T,Takasita M,et al.Evaluation of the risk of instrumentation as a foreign body in spinal tuberculosis. Clinical and biologic study.Spine (Phila Pa 1976). 1993;18(13): 1890-1894.

[24] 矢庆明,殷明,顾玉荣,等.脊柱结核植入内固定安全性的体外实验研究[J].实用临床医学,2012,13(8):1-6.

[25] 张小飞,施红光,赵剑.脊柱结核内固定的生物学基础[J].实用骨科杂志,2012,18(4):321-322.

[26] Liu X,Wu S,Yeung KW,et al.Relationship between osseointegration and superelastic biomechanics in porous NiTi scaffolds.Biomaterials.2011;32(2):330-338.

[27] Wu S,Liu X,Yeung KW,et al.Hydrogen release from titanium hydride in foaming of orthopedic NiTi scaffolds.Acta Biomater. 2011;7(3):1387-1397.

[28] 王挺锐,孟志斌,李俊.人工珊瑚骨治疗脊柱结核临床观察[J].中国热带医学,2008,8(9):1526.

[29] 郭新军,朱振军.人工珊瑚骨内固定手术治疗脊柱结核的临床效果分析[J].现代预防医学,2012,39(10):244-245.

[30] 山富彦.不同植骨材料联合钉棒系统在胸腰椎结核植骨融合术的应用和比较[J].实用医学杂志,2012,28(14):2416-2418.

[31] 张亚峰,王建伟,田小武,等.羟基磷灰石/丝蛋白复合骨材料应用于椎体间融合的研究[J].中华实验外科杂志,2009,26(4):542.

[32] 闵少雄,靳安民.聚DL-乳酸/羟基磷灰石复合材料修复长骨缺损的实验研究[J].中国临床解剖学杂志,2003,21(4):347-350.

[33] 张闻力,刘浩,李坛,等.医用硫酸钙人工骨在脊柱结核手术中的应用[J].中国矫形外科杂志, 2007,15(9):662-665.

[34] Bailey HL,Gabriel SM,Hodgson AR,et al.Tuberculosis of the spine in children. 1972 [classical article].Clin Orthop Relat Res.2002;(394):4-18.

[35] Wawro W,Konrad L,Aebi M.Single segment ingment internal fixator device in treatment of thoracolumbar vertebral fractures. Unfallchirurg.1994;97(3):114-120.

[36] 郑晨希,饶书城,牟至善.椎体钉在胸腰椎结核手术治疗中的应用[J].中华骨科杂志,1992,12(6): 401-404.

[37] 李伟,苏峰,张春林,等.单纯脊柱后路内固定治疗胸腰椎结核疗效探讨[J].河北医科大学学报,2014,55(9):1059-1062.

[38] 李诚，何大为，胡文．一期改良后路经单侧椎弓根入路病灶清除植骨内固定术治疗胸椎结核[J].中国修复重建外科杂志, 2011, 25(11):1294-1297.

[39] 张伟,徐勇.前后联合入路I期治疗脊柱结核的疗效[J].实用临床医学,2011,12(8):51-58.

[40] Heinig CF,Aoyd BM.One stage vertebreetomy or egg shell P dune.Orthop Trans.1985;9(11):130-135．

[41] Murrey DB,Brigham CD,kiebzak GM,et al.Transpedicular decompression and pedicle subtraction osteotomy(eggshell procedure):a retrospective review of 59 patients. Spine (Phila Pa 1976).2002;27(21):2338-2345.

[42] 张永刚,王岩,张雪松.单纯后路经椎弓根截骨或脊椎切除的临床分析[J].中华外科杂志,2007,45(8):525-528.