Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (52): 8396-8400.doi: 10.3969/j.issn.2095-4344.2015.52.006

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Bone cement and nano bone putty strengthen pedicle screw implantation in the fixation of osteoporotic vertebral body: biomechanical characteristics

Lu Xiao-bing1, Meng Xiang-xiang2   

  1. 1Changzhou No. 2 People’s Hospital Affiliated to Nanjing Medical University, Changzhou 213000, Jiangsu Province, China; 2Third Department of Orthopedics, Nanyang City Center Hospital, Nanyang 473000, Henan Province, China
  • Received:2015-11-08 Online:2015-12-17 Published:2015-12-17
  • About author:Lu Xiao-bing, Master, Associate chief physician, Changzhou No. 2 People’s Hospital Affiliated to Nanjing Medical University, Changzhou 213000, Jiangsu Province, China
  • Supported by:

    Open Project of CAD & CG State Key Laboratory in Zhejiang University of China, No. A1405

Abstract:

BACKGROUND: Nano bone putty and bone cement injection are two common methods to strengthen the fixation of pedicle screws, but there are relatively few reports on the comparison of their strengthening effects.
OBJECTIVE: To compare the biomechanical characteristics of bone cement and nano bone putty strengthening pedicle screw implantation in the fixation of osteoporotic vertebral body.
METHODS: Totally 24 human cadaveric pedicles were obtained, which were all in line with osteoporosis standards, and randomly divided into 3 groups: control group (only implanted pedicle screws), bone cement group (first injected bone cement in the nail channel, and then implanted pedicle screws) and nano bone putty group (first injected nano bone putty in the nail channel, and then implanted pedicle screws). After 2 hours of implantation, the maximum axial pullout strength and the maximum rotation torque of specimens in each group were determined.
RESULTS AND CONCLUSION: The maximum axial pullout strength and maximum rotation torque of the bone cement and the nano bone putty groups were greater than those of the control group (P < 0.05), and the      maximum axial pullout strength and the maximum rotation torque of the bone cement group were greater than those of the nano bone putty group (P < 0.05). These results demonstrate that the maximum axial pullout strength and the maximum rotation torque of pedicle screw implantation in the fixation of osteoporotic vertebral body can be effectively improved by injection of bone cement and nano bone putty, and the strengthening effect of bone cement is more obvious. 

 

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