Effect of warm needling on histomorphology of compressed lumbar nerve root in rats

doi:10.3969/j.issn.2095-4344.2015.49.001

Abstract

Abstract:

BACKGROUND: 80% of patients with early-stage lumbar disc herniation can be alleviated or cured by non-surgical treatment. Acupuncture is one of the very important non-surgical treatments, and has a definite therapeutic effect. Warm needling is an important part of acupuncture and moxibustion and exhibits the dual effects of acupuncture and moxibustion, including promoting coordination between Qi and blood, dredging the meridian passage and removing blood stasis to alleviate pain.
OBJECTIVE: To observe the effect of warm needling on histomorphology of compressed lumbar nerve root compression in rat models.
METHODS: Sixty Sprague-Dawley rats were divided into five groups: normal, model, meloxicam, acupuncture and warm needling groups (n=12 rats/group). A special silicone sheet was placed on the right side of the dural sac at the L5 nerve root to establish rat models of lumbar nerve root compression. Rats in normal group were not subjected to model establishment and treatment. Rats in model group were subjected to model establishment, but without treatment. Rats in meloxicam group were given the meloxicam treatment for 2 weeks after modeling. Rats in acupuncture group were given 2 weeks of acupuncture treatment after modeling. Rats in warm needling group were given 2 weeks of warm needling treatment after modeling. At 2 weeks after modeling, compressed lumbar nerve root tissue was harvested and stained with hematoxylin-eosin for histomorphological observation.
RESULTS AND CONCLUSION: At 2 weeks after rat models of lumbar nerve root compression were successfully established, as confirmed by pathological observation of nerve root section. Inflammatory response in the tissue surrounding the nerve fibers and dorsal root ganglia in the warm needling group better improved than in the meloxicam and acupuncture groups. These results suggest that compared with meloxicam and acupuncture, warm needling can more effectively improve the damaged rat nerve root structure and reduce the inflammatory response in rats with lumbar nerve root compression.

中国组织工程研究杂志出版内容重点：肾移植；肝移植；移植；心脏移植；组织移植；皮肤移植；皮瓣移植；血管移植；器官移植；组织工程

CLC Number:

R318

Xie Yan-yan, Wu Yao-chi. Effect of warm needling on histomorphology of compressed lumbar nerve root in rats[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(49): 7878-7878.

Figures/Tables 1

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