Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (26): 4127-4131.doi: 10.3969/j.issn.2095-4344.2015.26.006

Previous Articles     Next Articles

Relevant factors of survival within 1 year of femoral head replacement in aged patients 

Zhang Dang-feng1, Ma Wei1, Ge Zhao-hui2, Zhang Fei3, Guo Chi-hua1   

  1. 1Department of Orthopedics, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China; 2Department of Spine Surgery, Affiliated Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China; 3Department of Orthopedics, the Third Affiliated Hospital of Inner Mongolia Medical University, Baotou 014000, Inner Mongolia Autonomous Region, China)
  • Received:2015-05-23 Online:2015-06-25 Published:2015-06-25
  • Contact: Ma Wei, M.D., Chief physician, Department of Orthopedics, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China
  • About author:Zhang Dang-feng, Studying for doctorate, Attending physician, Department of Orthopedics, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China
  • Supported by:

    the National Natural Science Foundation of China, No. 30960391

Abstract:

BACKGROUND: The age, complication, injury to operation time, and pain level are important factors that affect patients with postoperative mortality, but many scholars disagree. Factors affecting death in elderly patients after femoral head replacement still need further study.
OBJECTIVE: To observe factors related to the survival status of elderly patients within 1 year after receiving femoral head replacement.
METHODS: A total of 96 elderly patients receiving femoral head replacement at Department of Orthopedics, the First Affiliated Hospital of Xi’an Jiaotong University from January 2011 to January 2014 were selected. On admission, patients’ age, sex, time from injury to operation, injury to admission time, pain classification, admission hemoglobin, serum albumin content of admission, admission lymphocyte count, and the amount of blood transfusion and preoperative complications were recorded. Fisher test was used to analyze the factors affecting survival status within 1 year after replacement in patients with femoral head replacement using one-way analysis of variance. Multivariate Cox test was utilized to perform multi-factor analysis.
RESULTS AND CONCLUSION: The injury to hospital time was > 5 days. Pain classification was grades III and IV. The hemoglobin content was < 120 g/L on admission. The volume of blood transfusion was > 1 000 mL. Serum albumin content was < 35 g/L, which was associated with the increased mortality (P < 0.05). The mortality was significantly higher in patients with more than 86 years old than in patients with 70-85 years old (P < 0.05). The mortality of patients with the time from injury to operation > 7 days was significantly higher than patients with the time from injury to operation < 7 days (P < 0.05). The serum albumin content < 35 g/L and grades III and IV of ASA classification were factors related to patient’s death (P < 0.05). Results confirm that the risk factors for survival status within 1 year of femoral head replacement contain intraoperative volume of blood transfusion, admission to operation time, hemoglobin content, and grading of pain.
 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Tissue Engineering, Femur Head, Pain

CLC Number: