Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (16): 2473-2478.doi: 10.3969/j.issn.2095-4344.2015.16.003

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Innova 3D-guided percutaneous vertebraplasty puncture reduces bone cement breakage

Li Song-hua, Yang Kai, Shen Yu-lan, Tian Qing-hua, Wu Chun-gen   

  1. Department of Interventional Radiology, Shanghai Sixth People’s Hospital, Shanghai 201306, China
  • Received:2015-03-13 Online:2015-04-16 Published:2015-04-16
  • Contact: Wu Chun-gen, Department of Interventional Radiology, Shanghai Sixth People’s Hospital, Shanghai 201306, China
  • About author:Li Song-hua, Technician, Department of Interventional Radiology, Shanghai Sixth People’s Hospital, Shanghai 201306, China

Abstract:

BACKGROUND: Percutaneous vertebraplasty is a new means for the treatment of vertebral compression fractures and bone metastases. The multiplaner reconstruction with digital substraction angiography (DSA)-Innova 3D plays an important role in guiding the percutaneous vertebraplasty puncture, which can effectively prevent the leakage of bone cement.
OBJECTIVE: To explore the value of DSA-Innova 3D in the guidance of puncture of percutaneous vertebroplasty.
METHODS: From March 2014 to September 2014, a total of 72 patients with 94 vertebras were selected for percutaneous vertebraplasty, of whom 36 (48 vertebras) with Innova 3D (experimentalgroup) and 36 (46 vertebras) without Innova 3D (control group). Spiral CT scan was performed in all patients to assess the distribution of bone cement. The imaging quality in the two groups was compared by Mann-Whitney U test.
RESULTS AND CONCLUSION: CT showed bone cement leakage occurred in 7 of the 36 patients in the control group. Leakages were into the lumber disc in two cases, paravertebral space in two cases, vertebral pedicle in one case or veins in two cases. However, only one case of bone cement leakage was observed in the experimental group. With the guidance of DSA-Innova 3D, the experimental group had signficantly lower leakage and fluoroscopic time than the control group (P < 0.05). The multiplaner reconstruction with DSA-Innova 3D plays an important role in guiding the percutaneous vertebraplasty puncture, thereby effectively reducing the leakage of bone cement.


中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程


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Key words: Vertebraplasty, Angiography, Digital Subtraction, Imaging Processing, Computer-Assisted

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