Acute exercise leads to varying peptide YY levels in adults: a Meta-analysis

doi:10.3969/j.issn.2095-4344.2015.15.030

Abstract

Abstract:

BACKGROUND: Acute exercise is believed to regulate appetite and influence feeding behaviors by controlling the synthesis and secretion of gastrointestinal peptide hormones to regulate appetite and feeding behavior influence, but the small sample size leads to widely different results.
OBJECTIVE: To clarify the effect of acute exercise on peptide YY levels in adults using Meta-analysis method.
METHODS: A computer-based search of PubMed, Google Scholar, Sport Discus, Web of Knowledge and CNKI was performed for relevant articles published before January 2014. The literatures eligible were studied by evaluating the publication bias, checking the heterogeneity and analyzing the sensitivity by software of RevMan5.1.
RESULTS AND CONCLUSION: (1) There were a total of 188 participants in the 18 trials reported in 11 articles. The Meta-analysis results revealed a mean effect for acute exercise to increase peptide YY values (standardized mean difference=0.25, 95% confidence interval =0.05-0.46, P=0.01), and therefore, there was a significantly statistical difference in the peptide YY levels between the acute exercise group and control group (P < 0.05). Moreover, results from the sensitivity analysis showed no influences on the findings of Meta-analysis. (2) Five randomized controlled trails in the three included articles were related to peptide YY (3-36). There was a maximal heterogeneity among these studies; therefore, a random-effect model was utilized. The result revealed a mean effect for acute exercise to increase peptide YY (3-36) values (standardized mean difference =1.80, 95% confidence interval =0.27-3.32, P=0.02). The findings from this meta-analysis show that acute exercise may influence appetite by increasing levels of peptide YY in adults.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

全文链接：

Key words: Sports Medicine, Peptides, Appetite

CLC Number:

R318

Wu Na-na, Wang Ru, Wang Xue-qiang, Guan Yan-fei. Acute exercise leads to varying peptide YY levels in adults: a Meta-analysis[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(15): 2455-2460.

Figures/Tables 3

References

[1] Ballantyne GH. Peptide YY(1-36) and peptide YY(3-36): Part I. Distribution, release and actions. Obes Surg.2006;16(5):651-658.
[2] King NA, Blundell JE. High-fat foods overcome the energy expenditure induced by high-intensity cycling or running. Eur J Clin Nutr.1995;49(2):114-123.
[3] Schubert MM, Sabapathy S, Leveritt M, et al. Acute exercise and hormones related to appetite regulation: a meta-analysis. Sports Med.2014;44(3):387-403.
[4] Balaguera-Cortes L, Wallman KE, Fairchild TJ, et al.Energy intake and appetite-related hormones following acute aerobic and resistance exercise. Appl Physiol Nutr Metab.2011;36(6): 958-966.
[5] Broom DR, Batterham RL, King JA, et al. Influence of resistance and aerobic exercise on hunger, circulating levels of acylated ghrelin, and peptide YY in healthy males. Am J Physiol Regul Integr Comp Physiol.2009;296(1):R29-R35.
[6] Cooper JA, Watras AC, Paton CM, et al.Impact of exercise and dietary fatty acid composition from a high-fat diet on markers of hunger and satiety. Appetite.2011;56(1):171-178.
[7] Deighton K, Barry R, Connon CE, et al. Appetite, gut hormone and energy intake responses to low volume sprint interval and traditional endurance exercise. Eur J Appl Physiol.2013; 113(5):1147-1156.
[8] Kawano H, Mineta M, Asaka M, et al. Effects of different modes of exercise on appetite and appetite-regulating hormones. Appetite.2013;66:26-33.
[9] Kelly PJ, Guelfi KJ, Wallman KE, et al. Mild dehydration does not reduce postexercise appetite or energy intake. Med Sci Sports Exerc.2012;44(3):516-524.
[10] Larson-Meyer DE, Palm S, Bansal A, et al.Influence of running and walking on hormonal regulators of appetite in women. J Obes.2012;2012:730409.
[11] Martins C, Morgan LM, Bloom SR, et al. Effects of exercise on gut peptides, energy intake and appetite. J Endocrinol.2007; 193(2):251-258.
[12] Shorten AL, Wallman KE, Guelfi KJ. Acute effect of environmental temperature during exercise on subsequent energy intake in active men.Am J Clin Nutr.2009;90(5): 1215-1221.
[13] Ueda SY, Yoshikawa T, Katsura Y, et al.Changes in gut hormone levels and negative energy balance during aerobic exercise in obese young males.J Endocrinol.2009;201(1): 151-159.
[14] Wasse LK, Sunderland C, King JA, et al. Influence of rest and exercise at a simulated altitude of 4,000 m on appetite, energy intake, and plasma concentrations of acylated ghrelin and peptide YY. J Appl Physiol (1985).2012;112(4):552-559.
[15] Hagobian TA, Yamashiro M, Hinkel-Lipsker J, et al. Effects of acute exercise on appetite hormones and ad libitum energy intake in men and women. Appl Physiol Nutr Metab.2013; 38(1): 66-72.
[16] King JA, Wasse LK, Ewens J, et al. Differential acylated ghrelin, peptide YY3-36, appetite, and food intake responses to equivalent energy deficits created by exercise and food restriction. J Clin Endocrinol Metab.2011;96(4):1114-1121.
[17] Ueda SY, Yoshikawa T, Katsura Y, et al. Comparable effects of moderate intensity exercise on changes in anorectic gut hormone levels and energy intake to high intensity exercise. J Endocrinol.2009;203(3):357-364.
[18] le Roux CW, Batterham RL, Aylwin SJ, et al. Attenuated peptide YY release in obese subjects is associated with reduced satiety. Endocrinology.2006;147(1):3-8.
[19] Korner J, Bessler M, Cirilo LJ, et al. Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin, peptide YY, and insulin. J Clin Endocrinol Metab.2005;90(1):359-365.
[20] Batterham RL, Cohen MA, Ellis SM, et al. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med. 2003;349(10): 941-948.
[21] Roth CL, Enriori PJ, Harz K, et al.Peptide YY is a regulator of energy homeostasis in obese children before and after weight loss. J Clin Endocrinol Metab. 2005;90(12): 6386-6391.
[22] le Roux CW, Batterham RL, Aylwin SJ, et al. Attenuated peptide YY release in obese subjects is associated with reduced satiety. Endocrinology.2006;147(1): 3-8.
[23] Karra E, Batterham RL. The role of gut hormones in the regulation of body weight and energy homeostasis. Mol Cell Endocrinol.2010;316(2): 120-128.
[24] Gibbons C, Caudwell P, Finlayson G, et al. Comparison of postprandial profiles of ghrelin, active GLP-1, and total PYY to meals varying in fat and carbohydrate and their association with hunger and the phases of satiety. J Clin Endocrinol Metab. 2013;98(5): E847-E855.