Four risk factors of deep venous thrombosis in lower limbs after total hip arthroplasty

doi:10.3969/j.issn.2095-4344.2015.13.001

Abstract

Abstract:

BACKGROUND: Deep venous thrombosis is one of the most common and dangerous complication. There will be serious consequences for failing to prevent deep venous thrombosis in advance, so we need to evaluate the risk factors of deep venous thrombosis.
OBJECTIVE: To evaluate the clinical risk factors for lower limb deep vein thrombosis after total hip arthroplasty.
METHODS: Data of 162 patients who were treated from January 2010 to February 2013 in Department of Bone and Joint Surgery, Shenzhen Hospital of Peking University for total hip arthroplasty were analyzed retrospectively. All patients received ultrasonography on deep veins of lower limb preoperatively and postoperatively 3 and 7 days. Risk factors of deep venous thrombosis were analyzed using Logistic regression analysis in patients undergoing total hip arthroplasty.
RESULTS AND CONCLUSION: The selected factors for Logistic regression model contained bone cement prosthesis, age distribution, body mass index, and general anesthesia. Their OR values were 9.215, 11.247, 3.842, 4.825, respectively. They were risk factors for the occurrence of deep venous thrombosis. Above results indicated that use of bone cement prosthesis, age, body mass index > 25 kg/m2 and general anesthesia are risk factors for deep venous thrombosis after total hip replacement, so they should cause clinical attention and we should take active measures to prevent them.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

全文链接：

Key words: Arthroplasty, Replacement, Hip, Venous Thrombosis, Hip Prosthesis

CLC Number:

R318

Zhang Sheng, Xie Xiao-chen, Yao Yue-feng, Wei Liang-chen. Four risk factors of deep venous thrombosis in lower limbs after total hip arthroplasty[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(13): 1969-1973.

Figures/Tables 2

References

[1] 李亮,赵阳,王志强.多孔金属钽髋臼在全髋关节置换术后髋臼翻修中的应用[J].中国骨与关节杂志, 2013, 2(8):470-473.
[2] 王睿铸,纪斌平,杨贵成.特殊髋关节义体术前测量的临床体会[J]. 实用医技杂志, 2014, 21(3):301-302.
[3] 刘辉,张育明,姚建锋,等.两种评估方法在全髋关节置换术后的比较研究[J].中国骨与关节外科,2011,4(6):450-454.
[4] 姜宇,杨玉生,朱国兴,等.中年患者128例生物型全髋置换和骨水泥全髋置换后的随访比较[J].中国组织工程研究,2012,16(17): 3069-3072.
[5] 钟群杰,林剑浩,武迎宏. 2010年北京地区全髋关节置换术手术部位感染目标性监测分析[J].中华医院感染学杂志,2012, 22(16): 3517-3520.
[6] 杨秋军,方玲,郝占元,等.全髋关节置换术后假体松动原因分析及防治[J].中国煤炭工业医学杂志,2013,16(9):1572-1574.
[7] 曾容.早期功能锻炼对髋关节置换术后深静脉血栓的预防效果观察[J].实用心脑肺血管病杂志,2014,22(8):55-56.
[8] 韩艳.人工膝髋关节置换术后下肢深静脉栓塞的预防[J].陕西医学杂志,2011,40(2):232-233.
[9] 尹知训.骨科大手术后静脉血栓栓塞症预防的进展[J].中华关节外科杂志:电子版,2012, 6(6):971-975.
[10] 吕厚山,徐斌.人工关节置换术后下肢深静脉血栓形成[J].中华骨科杂志,1999,19(3):155-156.
[11] 刘俊,赵银必,周忠华,等.骨科创伤手术后患者并发下肢深静脉血栓的预防和治疗[J].中国美容医学, 2014,4(16):240-241.
[12] 刘洪.下肢深静脉血栓形成的治疗进展[J].海南医学,2005,16(10): 153-155.
[13] 董尔丹,石山.血栓的实验方法与评价[J].中国药理学通报,1992, 8(6):422.
[14] 段曼,杜建时,马鹰,等. ABO血型与患者下肢深静脉血栓形成的关系[J].中国老年学杂志,2014,34(18):5265-5266.
[15] 柳剑,李玉军.静脉血栓栓塞症的物理预防[J].中华关节外科杂志:电子版,2012,6(2):329-333.
[16] 盛颂颂.下肢深静脉血栓形成的诊断和治疗进展[J].上海医药，2013,34(2):37-39.
[17] 刘畅,刘玉杰.骨科患者深静脉血栓形成危险因素与预防的研究进展[J].中国全科医学,2013,16(2):593-597.
[18] 张金辉,冯曜宇,金辉.静脉血栓栓塞患者携带Leiden V因子杂合子病例报告[J].中国血管外科杂志:电子版,2014,7(3):170-174.
[19] 李洁,辛晓敏,刘娅娜.血浆蛋白C、蛋白S在静脉血栓病人诊断及治疗中的应用[J]. 微循环技术杂志:临床与实验, 2004, 8(5): 317.
[20] 潘以锋,孙敏莉,张皓,等.深静脉血栓形成与凝血因子Ⅷ及蛋白C、蛋白S的相关性[J].中华实验外科杂志,2010,27(5):575-576.
[21] 李方超,靳会敏,佟倩.静脉血栓栓塞症患者蛋白C和蛋白S基因单核苷酸多态性分析[J].中国老年学杂志, 2014,34(3):859-860.
[22] 程志鹏,唐亮,陆铉,等.遗传性抗凝血酶及遗传性蛋白C联合缺乏症家系研究[J].临床血液学杂志,2014,27(3):375-378.
[23] 李蕾,王培昌.蛋白C抗凝系统及生物学作用最新研究进展[J].四川医学,2012,33(9):1685-1686.
[24] 刘芳,诸兰艳,陈平,等.蛋白C、蛋白S缺乏症相关肺动脉血栓栓塞2例并文献复习[J].中南大学学报,2013,38(9):971-976.
[25] Watanabe H, Takahashi K, Takenouchi K, et al. Pseudotumor an-d deep venous thrombosis due to crevice corrosion of the head–ne-ck junction in metal-on-polyethylene total hip arthroplasty. J Orthop Sci. 2014. [Epub ahead of print]
[26] 王艳红,马平.麻醉对髋关节置换术后深静脉血栓形成的影响[J]. 实用骨科杂志,2006,12(2):137-140.
[27] 李光辉,李锋,陈超,等.麻醉方式对全髋关节置换术后深静脉血栓形成的影响[J].中国矫形外科杂志,2003,11(21):1-2.
[28] 顾海伦,王欢,段景柱.人工全髋关节置换术后下肢深静脉血栓形成的多因素分析[J].中国骨伤, 2007,20(9):611-613.
[29] 唐孝明,裴福兴,沈彬.麻醉对人工全髋置换术后深静脉血栓形成的影响[J].中国骨与关节损伤杂志,2002,17(3):201-202.
[30] Semchuk W, Backstein D, Komari N, et al. Adherence with inje-ctable prophylaxis for venous thromboembolism (VTE) following to-tal hip (THR) and total knee (TKR) replacement surgery: complete registry. Res Matt.2013:28.
[31] 魏亦兵,夏军,王思群,等.综合预防全髋关节置换术后深静脉血栓形成的发生[J].中华关节外科杂志:电子版,2011,5(2):236-239.
[32] Meftah M, John M, Lendhey M, et al.Safety and Efficacy of Non-Cemented Femoral Fixation in Patients 75 Years of Age and Older. J Arthroplasty. 2013;28(8):1378-1380.
[33] 万仑,胡豇,刘仲前.骨水泥对全髋置换术后深静脉血栓形成的影响[J].四川医学,2002,23(8):798-799.
[34] 陈东峰,白波,卢伟杰,等.骨水泥激活兔血小板促进下肢深静脉血栓形成的实验研究[J]. 中华关节外科杂志(电子版),2007, 1(1): 42-44.
[35] 马骊,王欣,蒋丽华.人工髋关节置换后的深静脉血栓形成:发生因素及其预防策略[J].中国组织工程研究与临床康复,2010, 14(9): 1677-1680.
[36] 马俊,沈彬,杨静,等.人工全髋关节置换术后下肢深静脉血栓形成的危险因素分析[J].中国矫形外科杂志,2009,17(13):965-969.
[37] 温辉林,王友华,顾永强,等.全髋关节置换术后深静脉血栓形成的危险因素分析[J].江苏医药,2009,35(2):84-87.
[38] 查振刚,臧学慧,姚平,等.全髋关节置换术后深静脉血栓形成的临床研究及危险因素分析[J].中华外科杂志, 2005, 43(8):511-512.
[39] 张清,杨静,裴福兴,等.75 岁以上老年患者髋关节置换围术期合并症的处理及安全性评估[J].中国骨与关节杂志,2014, 13(6): 408-413.
[40] 张劲松,李琳.老年人静脉血栓栓塞症的流行病学[J].实用老年医学, 2013,28(10):806-809.