Orthodontic surgery with alveolar cleft grafting in patients with complete unilateral cleft lip and palate: a feasibility analysis based on cone-beam CT three-dimensional reconstruction

doi:10.3969/j.issn.2095-4344.2015.11.008

Abstract

Abstract:

BACKGROUND: Some cleft lip and palate patients at 9-10 years of age (the canine root development about 1/2-2/3) cannot achieve a good orthodontic outcome after bone grafting, and moreover, there is no unified therapeutic procedure for patients at 7-10 years of age before and after bone grafting. Cone-beam CT can reflect the fine structure accurately under the premise not to destroy normal tissue structure, and have access to the relevant measurement data by matched computer software.

OBJECTIVE: To compare the therapeutic effect of orthodontic surgery combined with alveolar cleft bone grafting at different order for treatment of complete unilateral cleft lip and palate.

METHODS: Sixty patients with complete unilateral cleft lip and palate admitted at Cangzhou People’s Hospital from 2012 to 2013 were enrolled and divided into three groups with 20 in each group: group A, autologous iliac graft was done followed by 3 months of wearing orthodontic retainer; Group B, autologous iliac graft was done immediately after orthodontic treatment and then, orthodontic retainer was used for 3 consecutive months; group C, orthodontic retainer was used for 3 consecutive months following orthodontic treatment, and then, autologous iliac graft was performed followed by another 3 consecutive months of wearing orthodontic retainer.

RESULTS AND CONCLUSION: There were significant differences between groups A and C in terms of SNA, SNB, ANB, U1-NA and L1-NB (P < 0.01). Group B was significantly higher than the group A in SNB and L1/NB (P < 0.05). Compared with the group B, the SNB and U1/NA were reduced, while the SNA and L1/NB were increased significantly in the group C (P < 0.05). These findings indicate that for complete unilateral cleft lip and palate patients, the orthodontic treatment before and after bone grafting is better than simple pre- or post-grafting orthodontic treatment, which is conductive to the stability of corrected maxilla.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

全文链接：

Key words: Cleft Palate, Cleft Lip, Alveolar Process, Bone Transplantation

CLC Number:

R318

Shen Yue, Ma Hai-ying, Zhang Yan-sheng, Wang Juan, Shi Bing-zheng. Orthodontic surgery with alveolar cleft grafting in patients with complete unilateral cleft lip and palate: a feasibility analysis based on cone-beam CT three-dimensional reconstruction[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(11): 1678-1682.

Figures/Tables 4

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