Correlation of adjacent segment disease of L3-4 and gender after lumbar fusion

doi:10.3969/j.issn.2095-4344.2016.39.006

Abstract

Abstract:

BACKGROUND: Because of complicated biomechanics of lumbar vertebra, mast facet osteoarthritis, degenerative joint disease and vertebral subluxation usually occur following lumbar fusion. To avoid adjacent segment disease, researchers have transformed strong internal fixation into elastic fixation, but the treatment outcomes are barely satisfactory. Furthermore, factors involving adjacent segment disease remain unclear.

OBJECTIVE: To explore the relationship between L₃_-₄ segment disease following lumbar fusion and gender.

METHODS: 200 patients undergoing lumbar fusion of L₄_-₅and L₅-S₁ in the First Hospital of Shijiazhuang ranging from 2007 to 2016 were enrolled, and then allotted into male and female groups (n=100 per group) for retrospective analysis. The incidence of L₃_-₄segment disease was compared between two groups.

RESULTS AND CONCLUSION: Compared with the male group, in the female group, the incidence of L₃_-₄segment diseases at different fusion locations and ranges, the Oswestry disability index and visual analogue scale and each migration range were significantly higher. Logistic regression analysis showed that gender was one of the independent factors of L₃_-₄ segment disease following lumbar fusion of L₃_-₄ and L₅-S₁. These findings suggest that gender is one of the influencing factors of L₃_-₄ segment disease after instrumented lumbar; thereby, adjacent segment disease occurs frequently in female patients.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Lumbar Vertebrae, Bone Transplantation, Tissue Engineering

CLC Number:

R318

Wang Zhao-jun, Feng Yan-hong, Zhang Xiao-li, Du Shu-juan, Wang Xi, Zhang Shuang-wei, Fan Jin-peng, Xu Feng-zhou, Wang Wei-jiang . Correlation of adjacent segment disease of L_3-4 and gender after lumbar fusion

[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(39): 5813-5818.

Figures/Tables 5

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