Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (44): 7122-7126.doi: 10.3969/j.issn.2095-4344.2014.44.013

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Intervertebral fusion cage combined with pedicle screw systems for the treatment of lumbar isthmic spondylolisthesis: evaluation of the intervertebral space height

Mi Dong, Yang Ming-kun, Zhang Xu, Wu Ji-sheng, Liu Chuan, Li Zhou, Wang Jie   

  1. Department of Orthopedics, Bazhong Central Hospital, Bazhong 636000, Sichuan Province, China
  • Online:2014-10-22 Published:2014-10-22
  • About author:Mi Dong, Attending physician, Department of Orthopedics, Bazhong Central Hospital, Bazhong 636000, Sichuan Province, China

Abstract:

BACKGROUND: The main treatment of lumbar isthmic spondylolisthesis is the surgery, in a broader attempt to decompression, reduction, fixation and fusion of the lesioned segments. The golden standard of the treatment is biological fusion, while internal fixation is a reliable assistance for fusion therapy.
OBJECTIVE: To discuss the clinical value and curative effect of intervertebral fusion cage combined with pedicle screw systems for the treatment of lumbar isthmic spondylolisthesis.
METHODS: From March 2010 to March 2013, 21 cases of isthmic spondylolisthesis were treated with intervertebral fusion cage combined with pedicle screw systems, including 18 cases of spondylolisthesis of degree II and 3 cases of spondylolisthesis of degree III. All patients were followed up regularly, taking JOA lumbago score and visual analog scale score as the objective evaluation criteria of pain in postoperative follow-ups. The curative effect was assessed by Macrab standard, and the functional recovery was evaluated based on indicators such as Prolo, and the spinal fusion rate was assessed according to Lenke criteria. Changes of slippage rate, slippage angle, sacral inclination angle and intervertebral space post height in preoperative and postoperative periods were evaluated by iconography data.
RESULTS AND CONCLUSION: All the 21 patients with isthmic spondylolisthesis were followed up for 12-16 months. JOA lumbago score and vasual analog scale score of all patients were improved after treatment, and the  difference was statistically significant compared with before treatment (P=0.000). According to Macrab evaluation criteria, there were 17 excellent cases and 4 good cases. Each indicator evaluated by preoperative Prolo activities and symptom grading showed significant differences in preoperative and postoperative periods (P=0.003). Postoperative lumbar spondylolisthesis was basically reset, the slippage angle was significantly reduced, the sacral inclination angle was increased, and the height of the intervertebral space was recovered basically. Intervertebral fusion cage combined with pedicle screw systems was one of the effective strategies to treat lumbar isthmic spondylolisthesis.


中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程


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Key words: internal fixator, spondylolysis, lumbar vertebra, pain determination

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