Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (9): 1651-1655.doi: 10.3969/j.issn.1673-8225.2012.09.031

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Anterior cervical decompression plus MC+® cervical fusion cage versus anterior corpectomy plus titanium plate internal fixation for treatment of single-level cervical spondylotic myelopathy

He Bin1, Fan Lei2, Cheng Wei-nan1, Wang Yun-hua1, Wang Bo-yao1, Liu Jun1, Huang Ye1   

  1. 1Department of Orthopaedics, the Second Affiliated Hospital of Nanjing Medical University, Nanjing  210011, Jiangsu Province, China; 2Department of Orthopaedics, Wuhan Union Hospital, Huazhong University of Science and Technology, Wuhan  430022, Hubei Province, China
  • Received:2011-08-10 Revised:2011-09-28 Online:2012-02-26 Published:2012-02-26
  • Contact: Wang Yun-hua, Chief physician, Department of Orthopaedics, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China
  • About author:He Bin★, Master, Attending physician, Lecturer, Department of Orthopaedics, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China hbnj0016@sohu.com

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Abstract:

BACKGROUND: Anterior cervical decompression and fusion has become the golden standard of anterior cervical surgery for the treatment of cervical spondylotic myelopathy (CSM). But for single level CSM, whether fixation is needed remains controversial. Cervical cage fusion combined with bone grafting plays a very important role in treating single-level CSM in recent years.
OBJECTIVE: To compare the clinical curative effects of anterior decompression and implantation of MC+® cervical intervertebral fusion cage combined with bone grafting with anterior cervical vertebrectomy and fixation of titanium plate on the treatment of single-level CSM.
METHODS: Totally 42 single-level CSM patients were randomly divided into two groups. Patients treated by anterior decompression and implantation of MC+® cervical intervertebral fusion cage combined with bone grafting were taken as experimental group. Patients in control group were treated by anterior corpectomy and titanium plate internal fixation combined with bone grafting.
RESULTS AND CONCLUSION: The postoperative Japanese Orthopedic Association (JOA) scores and cervical curvature improved obviously in both groups (P < 0.05). All cases were followed up for 12-29 months. At six months after surgery and the final follow-up, the JOA scores and the cervical curvature showed no significant differences from those postoperatively (P > 0.05). The JOA scores and cervical curvature showed no statistical differences between the two groups prior to and after surgery as well as at each follow-up (P > 0.05). At the final follow-up, the fusion rate was 100%, neither of the groups had implantation loosening or protrusion. After operation, one case of hoarseness occurred in the experimental group, and in the control group there were one case of hoarseness, three cases of dysphagia, and two cases of esophageal injury. The results indicated that both of the two surgical methods have reliable clinical outcomes for single-level CSM; however, the former one is simpler and has fewer early complications.

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